PURPOSE: The purpose of this study was to determine whether dynamic helical computed tomography (CT)-mammography could assist in selecting the most appropriate surgical method in women with breast cancer. MATERIALS AND METHODS: Preoperative contrast-enhanced helical CT scanning of the breast was performed on 133 female patients with suspicion of breast cancer at the same time as clinical, mammographic, and/or ultrasonographic examinations. The patients were scanned in the prone position with a specially designed CT-compatible device. A helical scan was made with rapid intravenous bolus injection (3 ml/s) of 100 ml of iodine contrast material. Three-dimensional maximum intensity projection (MIP) images were reconstructed, and CT findings were correlated with surgical and histopathological findings. RESULTS: Histopathological analysis revealed 84 malignant lesions and seven benign lesions. The sensitivity, specificity, and accuracy levels of the CT scanning were 94.6%, 58.6%, and 78.9%. Helical scanning alone revealed additional contralateral carcinomas in three of four patients and additional ipsilateral carcinomas in three of five patients. However, the technique gave false-positive readings in 24 patients. The preoperative CT-mammogram altered the surgical method in six patients. CONCLUSION: Dynamic helical CT-mammography in the prone position may be one of the choices of adjunct imaging in patients with suspected breast cancer scheduled for surgery.
PURPOSE: The purpose of this study was to determine whether dynamic helical computed tomography (CT)-mammography could assist in selecting the most appropriate surgical method in women with breast cancer. MATERIALS AND METHODS: Preoperative contrast-enhanced helical CT scanning of the breast was performed on 133 female patients with suspicion of breast cancer at the same time as clinical, mammographic, and/or ultrasonographic examinations. The patients were scanned in the prone position with a specially designed CT-compatible device. A helical scan was made with rapid intravenous bolus injection (3 ml/s) of 100 ml of iodine contrast material. Three-dimensional maximum intensity projection (MIP) images were reconstructed, and CT findings were correlated with surgical and histopathological findings. RESULTS: Histopathological analysis revealed 84 malignant lesions and seven benign lesions. The sensitivity, specificity, and accuracy levels of the CT scanning were 94.6%, 58.6%, and 78.9%. Helical scanning alone revealed additional contralateral carcinomas in three of four patients and additional ipsilateral carcinomas in three of five patients. However, the technique gave false-positive readings in 24 patients. The preoperative CT-mammogram altered the surgical method in six patients. CONCLUSION: Dynamic helical CT-mammography in the prone position may be one of the choices of adjunct imaging in patients with suspected breast cancer scheduled for surgery.
Authors: F Sardanelli; M Calabrese; F Zandrino; E Melani; R Parodi; A Imperiale; T Massa; G Parodi; G Canavese Journal: J Comput Assist Tomogr Date: 1998 May-Jun Impact factor: 1.826
Authors: S E Harms; D P Flamig; K L Hesley; M D Meiches; R A Jensen; W P Evans; D A Savino; R V Wells Journal: Radiology Date: 1993-05 Impact factor: 11.105
Authors: C H Chang; D E Nesbit; D R Fisher; S L Fritz; S J Dwyer; A W Templeton; F Lin; W R Jewell Journal: AJR Am J Roentgenol Date: 1982-03 Impact factor: 3.959
Authors: S H Heywang; D Hahn; H Schmidt; I Krischke; W Eiermann; R Bassermann; J Lissner Journal: J Comput Assist Tomogr Date: 1986 Mar-Apr Impact factor: 1.826
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Authors: Vera Froeling; Felix Diekmann; Diane M Renz; Eva M Fallenberg; Ingo G Steffen; Susanne Diekmann; Rüdiger Lawaczeck; Florian F Schmitzberger Journal: Eur Radiol Date: 2013-01-10 Impact factor: 5.315