Literature DB >> 16713947

Eukaryotic transcription: what does it mean for a gene to be 'on'?

Ido Golding1, Edward C Cox.   

Abstract

Until recently, transcription could only be observed by measuring mRNA production of cell populations, thus obscuring the kinetics at the level of individual transcription events. A new study now shows that eukaryotic transcription, visualised in individual living cells, occurs in bursts -- much as it does in prokaryotes.

Mesh:

Year:  2006        PMID: 16713947     DOI: 10.1016/j.cub.2006.04.014

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  11 in total

Review 1.  Transcriptional activators and activation mechanisms.

Authors:  Jun Ma
Journal:  Protein Cell       Date:  2011-12-17       Impact factor: 14.870

2.  Gene-gene cooperativity in small networks.

Authors:  Aleksandra M Walczak; Peter G Wolynes
Journal:  Biophys J       Date:  2009-06-03       Impact factor: 4.033

3.  Somitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock protein.

Authors:  Mark Campanelli; Tomás Gedeon
Journal:  PLoS Comput Biol       Date:  2010-04-01       Impact factor: 4.475

4.  Quantifying extrinsic noise in gene expression using the maximum entropy framework.

Authors:  Purushottam D Dixit
Journal:  Biophys J       Date:  2013-06-18       Impact factor: 4.033

5.  A continuum model of transcriptional bursting.

Authors:  Adam M Corrigan; Edward Tunnacliffe; Danielle Cannon; Jonathan R Chubb
Journal:  Elife       Date:  2016-02-20       Impact factor: 8.140

Review 6.  Complex dynamics of transcription regulation.

Authors:  Diana A Stavreva; Lyuba Varticovski; Gordon L Hager
Journal:  Biochim Biophys Acta       Date:  2012-03-28

7.  Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene.

Authors:  Chenghang Zong; Lok-hang So; Leonardo A Sepúlveda; Samuel O Skinner; Ido Golding
Journal:  Mol Syst Biol       Date:  2010-11-30       Impact factor: 11.429

8.  General properties of transcriptional time series in Escherichia coli.

Authors:  Lok-Hang So; Anandamohan Ghosh; Chenghang Zong; Leonardo A Sepúlveda; Ronen Segev; Ido Golding
Journal:  Nat Genet       Date:  2011-05-01       Impact factor: 38.330

Review 9.  New methods to image transcription in living fly embryos: the insights so far, and the prospects.

Authors:  Teresa Ferraro; Tanguy Lucas; Marie Clémot; Jose De Las Heras Chanes; Jonathan Desponds; Mathieu Coppey; Aleksandra M Walczak; Nathalie Dostatni
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2016-02-19       Impact factor: 5.814

10.  Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.

Authors:  Weimin L Kaufman; Ibrahim Kocman; Vishal Agrawal; Hans-Peter Rahn; Daniel Besser; Manfred Gossen
Journal:  Nucleic Acids Res       Date:  2008-08-05       Impact factor: 16.971

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