Literature DB >> 16641463

Comparative in vitro efficacies of various catheter lock solutions.

Robert J Sherertz1, Michael S Boger, Casey A Collins, Lori Mason, Issam I Raad.   

Abstract

MEDTA (minocycline-edetate calcium disodium), taurolidine (2%)-polyvinylpyrolidine (5%) (T/PVP), and ethanol as potential catheter lock solutions have a unique mechanism of action, broad-spectrum activity, and anticoagulant properties. Traditional lock solutions minocycline (M), rifampin (R), ciprofloxacin (C), and vancomycin, except pharmacologic concentrations of C and R and of M and R, were less effective than MEDTA and T/PVP.

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Year:  2006        PMID： 16641463      PMCID： PMC1472229          DOI： 10.1128/AAC.50.5.1865-1868.2006

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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Review 3.  EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care.

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