| Literature DB >> 16630828 |
Benjamin Judkewitz1, Arnd Roth, Michael Häusser.
Abstract
It has been a longstanding challenge for experimentalists to manipulate precisely the spatial and temporal patterns of synaptic input to the dendritic tree in order to mimic activity occurring in the intact brain and determine their importance for synaptic integration. In this issue of Neuron, Losonczy and Magee have used rapid multisite two-photon uncaging of glutamate to define patterns of synaptic input on a submillisecond and micron scale to investigate the rules for summation of synaptic inputs in the fine oblique dendrites of pyramidal neurons.Entities:
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Year: 2006 PMID： 16630828 DOI： 10.1016/j.neuron.2006.04.011
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173