BACKGROUND: The epidemiology of patients with lung cancer in a Seine-Saint-Denis hospital are reported, as well as causes of diagnostic and therapeutic delays in their management. MATERIAL AND METHODS: Retrospective analysis of cases diagnosed from January 1, 1997 to December 31, 2003. RESULTS: Of 355 cases, 15.8% were women; the average age was 62 +/- 11. Mean smoking history was 50 +/- 24 pack years. Women were more likely to be non-smokers than men (16% and 1% respectively, p < 0.01) and were more likely to present at a young age (under the age of 50: 26.8% and 13.7% respectively, p < 0.05). Among women, adenocarcinoma was more frequent (41% vs. 25%, p < 0.05), and often presented with stage IV disease (74%). Squamous cell carcinoma occurred more frequently with increasing age (18.7% vs. 32.2% before and after the age of 60, p < 0.01). The median pre hospital, diagnostic and treatment delays were respectively 30, 10 and 9 days, the global delay from first symptom to treatment was 62 days. Surgery increased therapeutic delay by 20 days. CONCLUSION: Our results are complementary to those found in KBP-2000-CPHG study. Young women are diagnosed at a late stage. Influence of delays on prognosis is not proved and require others studies.
BACKGROUND: The epidemiology of patients with lung cancer in a Seine-Saint-Denis hospital are reported, as well as causes of diagnostic and therapeutic delays in their management. MATERIAL AND METHODS: Retrospective analysis of cases diagnosed from January 1, 1997 to December 31, 2003. RESULTS: Of 355 cases, 15.8% were women; the average age was 62 +/- 11. Mean smoking history was 50 +/- 24 pack years. Women were more likely to be non-smokers than men (16% and 1% respectively, p < 0.01) and were more likely to present at a young age (under the age of 50: 26.8% and 13.7% respectively, p < 0.05). Among women, adenocarcinoma was more frequent (41% vs. 25%, p < 0.05), and often presented with stage IV disease (74%). Squamous cell carcinoma occurred more frequently with increasing age (18.7% vs. 32.2% before and after the age of 60, p < 0.01). The median pre hospital, diagnostic and treatment delays were respectively 30, 10 and 9 days, the global delay from first symptom to treatment was 62 days. Surgery increased therapeutic delay by 20 days. CONCLUSION: Our results are complementary to those found in KBP-2000-CPHG study. Young women are diagnosed at a late stage. Influence of delays on prognosis is not proved and require others studies.
Authors: Francisco Javier González-Barcala; José María García-Prim; José Manuel Alvarez-Dobaño; Milagros Moldes-Rodríguez; María Teresa García-Sanz; Antonio Pose-Reino; Luis Valdés-Cuadrado Journal: Clin Transl Oncol Date: 2010-12 Impact factor: 3.405
Authors: F J Gonzalez-Barcala; J A Falagan; J M Garcia-Prim; L Valdes; J M Carreira; A Puga; P Martín-Lancharro; M T Garcia-Sanz; D Anton-Sanmartin; J C Canive-Gomez; A Pose-Reino; R Lopez-Lopez Journal: Ir J Med Sci Date: 2013-10-04 Impact factor: 1.568
Authors: Valéry Refeno; Nomeharisoa Rodrigue Emile Hasiniatsy; Ny Ony Tiana Florence Andrianandrasana; Andriatsihoarana Voahary Nasandratriniavo Ramahandrisoa; Jean Marc Rakotonarivo; Joée Larissa Maevazaka; Hanitrala Jean Louis Rakotovao; Florine Rafaramino Journal: Pan Afr Med J Date: 2015-11-20
Authors: Virginia Leiro-Fernández; Cecilia Mouronte-Roibás; Esmeralda García-Rodríguez; Maribel Botana-Rial; Cristina Ramos-Hernández; María Torres-Durán; Alberto Ruano-Raviña; Alberto Fernández-Villar Journal: Thorac Cancer Date: 2019-01-03 Impact factor: 3.500
Authors: Karam Yahya Belmokhtar; Mariam Tajir; Redouane Boulouiz; Amal Bennani; Sami Aziz Brahmi; Ihsan Alloubi; Hatim Kouismi; Imane Kamaoui; Imane Skiker; Said Afqir; Naima Abda; Mohammed Bellaoui; Loubna Mezouar Journal: Pan Afr Med J Date: 2019-12-05