Literature DB >> 16580505

Multiple regions-of-interest analysis of setup uncertainties for head-and-neck cancer radiotherapy.

Lifei Zhang1, Adam S Garden, Justin Lo, K Kian Ang, Anesa Ahamad, William H Morrison, David I Rosenthal, Mark S Chambers, X Ronald Zhu, Radhe Mohan, Lei Dong.   

Abstract

PURPOSE: To analyze three-dimensional setup uncertainties for multiple regions of interest (ROIs) in head-and-neck region. METHODS AND MATERIALS: In-room computed tomography (CT) scans were acquired using a CT-on-rails system for 14 patients. Three separate bony ROIs were defined: C2 and C6 vertebral bodies and the palatine process of the maxilla. Translational shifts of 3 ROIs were calculated relative to the marked isocenter on the immobilization mask.
RESULTS: The shifts for all 3 ROIs were highly correlated. However, noticeable differences on the order of 2-6 mm existed between any 2 ROIs, indicating the flexibility and/or rotational effect in the head-and-neck region. The palatine process of the maxilla had the smallest right-left shifts because of the tight lateral fit in the face mask, but the largest superior-inferior movement because of in-plane rotation and variations in jaw positions. The neck region (C6) had the largest right-left shifts. The positioning mouthpiece was found effective in reducing variations in the superior-inferior direction. There was no statistically significant improvement for using the S-board (8 out of 14 patients) vs. the short face mask.
CONCLUSIONS: We found variability in setup corrections for different regions of head-and-neck anatomy. These relative positional variations should be considered when making setup corrections or designing treatment margins.

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Year:  2006        PMID: 16580505     DOI: 10.1016/j.ijrobp.2005.12.023

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  51 in total

Review 1.  Current progress in adaptive radiation therapy for head and neck cancer.

Authors:  David L Schwartz
Journal:  Curr Oncol Rep       Date:  2012-04       Impact factor: 5.075

2.  Influence of the type of imaging on the delineation process during the treatment planning.

Authors:  Weronika Jackowiak; Bartosz Bąk; Anna Kowalik; Adam Ryczkowski; Małgorzata Skórska; Małgorzata Paszek-Widzińska
Journal:  Rep Pract Oncol Radiother       Date:  2015-06-18

3.  Variable planning margin approach to account for locoregional variations in setup uncertainties.

Authors:  Jinzhong Yang; Adam S Garden; Yongbin Zhang; Lifei Zhang; Lei Dong
Journal:  Med Phys       Date:  2012-08       Impact factor: 4.071

4.  Set-up errors and planning target volume margins in head and neck cancer radiotherapy: a clinical study of image guidance with on-line cone-beam computed tomography.

Authors:  Francesco Dionisi; Mauro Filippo Palazzi; Francesco Bracco; Maria Grazia Brambilla; Claudia Carbonini; Diego Dario Asnaghi; Angelo Filippo Monti; Alberto Torresin
Journal:  Int J Clin Oncol       Date:  2012-03-03       Impact factor: 3.402

5.  Measuring uncertainty in dose delivered to the cochlea due to setup error during external beam treatment of patients with cancer of the head and neck.

Authors:  M Yan; D Lovelock; M Hunt; J Mechalakos; Y Hu; H Pham; A Jackson
Journal:  Med Phys       Date:  2013-12       Impact factor: 4.071

6.  Correlation of PET images of metabolism, proliferation and hypoxia to characterize tumor phenotype in patients with cancer of the oropharynx.

Authors:  Matthew J Nyflot; Paul M Harari; Stephen Yip; Scott B Perlman; Robert Jeraj
Journal:  Radiother Oncol       Date:  2012-10-13       Impact factor: 6.280

7.  Adaptive radiation therapy for head and neck cancer-can an old goal evolve into a new standard?

Authors:  David L Schwartz; Lei Dong
Journal:  J Oncol       Date:  2010-08-18       Impact factor: 4.375

8.  Accurate positioning for head and neck cancer patients using 2D and 3D image guidance.

Authors:  Hyejoo Kang; Dale M Lovelock; Ellen D Yorke; Sergey Kriminski; Nancy Lee; Howard I Amols
Journal:  J Appl Clin Med Phys       Date:  2010-10-27       Impact factor: 2.102

9.  Patient positioning in head and neck cancer : Setup variations and safety margins in helical tomotherapy.

Authors:  Christina Leitzen; Timo Wilhelm-Buchstab; Thomas Müdder; Martina Heimann; David Koch; Christopher Schmeel; Birgit Simon; Sabina Stumpf; Susanne Vornholt; Stephan Garbe; Fred Röhner; Felix Schoroth; Hans Heinz Schild; Heinrich Schüller
Journal:  Strahlenther Onkol       Date:  2018-01-25       Impact factor: 3.621

10.  Recent advances in image-guided radiotherapy for head and neck carcinoma.

Authors:  Sameer K Nath; Daniel R Simpson; Brent S Rose; Ajay P Sandhu
Journal:  J Oncol       Date:  2009-07-29       Impact factor: 4.375

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