Literature DB >> 16572230

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.

Alison M Hill1.   

Abstract

This review covers the biosynthesis of aliphatic and aromatic polyketides as well as mixed polyketide/NRPS metabolites, and discusses the molecular genetics and enzymology of the proteins responsible for their formation.

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Year:  2005        PMID: 16572230     DOI: 10.1039/b301028g

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


  20 in total

1.  Structure-based dissociation of a type I polyketide synthase module.

Authors:  Alice Y Chen; David E Cane; Chaitan Khosla
Journal:  Chem Biol       Date:  2007-07

Review 2.  The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines.

Authors:  Adrian T Keatinge-Clay
Journal:  Chem Rev       Date:  2017-04-10       Impact factor: 60.622

3.  Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases.

Authors:  Woojoo E Kim; Ashay Patel; Gene H Hur; Peter Tufar; Michael G Wuo; J Andrew McCammon; Michael D Burkart
Journal:  Chembiochem       Date:  2018-11-09       Impact factor: 3.164

Review 4.  Unraveling polyketide synthesis in members of the genus Aspergillus.

Authors:  Yi-Ming Chiang; Berl R Oakley; Nancy P Keller; Clay C C Wang
Journal:  Appl Microbiol Biotechnol       Date:  2010-04-02       Impact factor: 4.813

5.  Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.

Authors:  Tonia J Buchholz; Todd W Geders; Frank E Bartley; Kevin A Reynolds; Janet L Smith; David H Sherman
Journal:  ACS Chem Biol       Date:  2009-01-16       Impact factor: 5.100

Review 6.  Biosynthesis and function of polyacetylenes and allied natural products.

Authors:  Robert E Minto; Brenda J Blacklock
Journal:  Prog Lipid Res       Date:  2008-03-13       Impact factor: 16.195

7.  An enzymatic cyclopentyl[b]indole formation involved in scytonemin biosynthesis.

Authors:  Emily P Balskus; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2009-10-21       Impact factor: 15.419

8.  Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.

Authors:  Fong T Wong; Alice Y Chen; David E Cane; Chaitan Khosla
Journal:  Biochemistry       Date:  2010-01-12       Impact factor: 3.162

Review 9.  The type I fatty acid and polyketide synthases: a tale of two megasynthases.

Authors:  Stuart Smith; Shiou-Chuan Tsai
Journal:  Nat Prod Rep       Date:  2007-07-02       Impact factor: 13.423

Review 10.  Accessing natural product biosynthetic processes by mass spectrometry.

Authors:  Stefanie B Bumpus; Neil L Kelleher
Journal:  Curr Opin Chem Biol       Date:  2008-10       Impact factor: 8.822

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