Literature DB >> 16562848

Tropane aromatic ester alkaloids from a large-scale re-collection of Erythroxylum pervillei stem bark obtained in Madagascar.

Young-Won Chin1, William P Jones, Timothy J Waybright, Thomas G McCloud, Philippe Rasoanaivo, Gordon M Cragg, John M Cassady, A Douglas Kinghorn.   

Abstract

Fractionation by pH zone-refining countercurrent chromatography of an extract of the stem bark of Erythroxylum pervillei, obtained on a kilogram scale in southern Madagascar, led to the isolation and characterization of four tropane aromatic ester alkaloids as minor constituents, namely, pervilleines G (5) and H (6) and cis-pervilleines B (7) and F (8). Their structures were determined by spectroscopic data interpretation.

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Year:  2006        PMID： 16562848      PMCID： PMC2614919          DOI： 10.1021/np050366v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype.

Authors:  Q Mi; B Cui; G L Silva; D Lantvit; E Lim; H Chai; M You; M G Hollingshead; J G Mayo; A D Kinghorn; J M Pezzuto
Journal:  Cancer Res       Date:  2001-05-15       Impact factor: 12.701

2.  Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei.

Authors:  G L Silva; B Cui; D Chávez; M You; H B Chai; P Rasoanaivo; S M Lynn; M J O'Neill; J A Lewis; J M Besterman; A Monks; N R Farnsworth; G A Cordell; J M Pezzuto; A D Kinghorn
Journal:  J Nat Prod       Date:  2001-12       Impact factor: 4.050

Review 3.  Chemotaxonomy and geographical distribution of tropane alkaloids.

Authors:  W J Griffin; G D Lin
Journal:  Phytochemistry       Date:  2000-03       Impact factor: 4.072

4.  Preparative separation of components of the color additive D&C Red No. 28 (phloxine B) by pH-zone-refining counter-current chromatography.

Authors:  A Weisz; D Andrzejewski; Y Ito
Journal:  J Chromatogr A       Date:  1994-08-26       Impact factor: 4.759

5.  Tropane alkaloids from the leaves and stem bark of Erythroxylon alaternifolium and Erythroxylon rotundifolium.

Authors:  A L Payo-Hill; R S Dominguez; M O Suarez; M Batista-Baez; H T Castro; L Rastrelli; R Aquino
Journal:  Phytochemistry       Date:  2000-08       Impact factor: 4.072

6.  Tropane alkaloids from the bark of Erythroxylum vacciniifolium.

Authors:  Boris Zanolari; David Guilet; Andrew Marston; Emerson F Queiroz; Marçal de Q Paulo; Kurt Hostettmann
Journal:  J Nat Prod       Date:  2003-04       Impact factor: 4.050

7.  Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium.

Authors:  Daniel Chávez; Baoliang Cui; Hee-Byung Chai; Ricardo García; Miliciades Mejía; Norman R Farnsworth; Geoffrey A Cordell; John M Pezzuto; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2002-04       Impact factor: 4.050

8.  Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance.

Authors:  Qiuwen Mi; Baoliang Cui; Daniel Lantvit; Eulenia Reyes-Lim; Heebyung Chai; John M Pezzuto; A Douglas Kinghorn; Steven M Swanson
Journal:  Anticancer Res       Date:  2003 Sep-Oct       Impact factor: 2.480

9.  Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay.

Authors:  Qiuwen Mi; Baoliang Cui; Gloria L Silva; Daniel Lantvit; Eula Lim; Heebyung Chai; Melinda G Hollingshead; Joseph G Mayo; A Douglas Kinghorn; John M Pezzuto
Journal:  Cancer Lett       Date:  2002-10-08       Impact factor: 8.679

10.  New tropane alkaloids from Erythroxylum moonii.

Authors:  Khanzadi Fatima Khattak; Mohammad Iqbal Choudhary; K D Hemalal; L M Tillekeratne
Journal:  J Nat Prod       Date:  2002-06       Impact factor: 4.050
  10 in total
  6 in total

Review 1.  The relevance of higher plants in lead compound discovery programs.

Authors:  A Douglas Kinghorn; Li Pan; Joshua N Fletcher; Heebyung Chai
Journal:  J Nat Prod       Date:  2011-06-08       Impact factor: 4.050

2.  Potentiating effect of the flavonolignan (-)-hydnocarpin in combination with vincristine in a sensitive and P-gp-expressing acute lymphoblastic leukemia cell line.

Authors:  Lynette Bueno Pérez; Li Pan; Ellen Sass; Sneha V Gupta; Amy Lehman; A Douglas Kinghorn; David M Lucas
Journal:  Phytother Res       Date:  2012-12-28       Impact factor: 5.878

3.  Evaluation of the cholinergic and adrenergic effects of two tropane alkaloids from Erythroxylum pervillei.

Authors:  Young-Won Chin; A Douglas Kinghorn; Popat N Patil
Journal:  Phytother Res       Date:  2007-10       Impact factor: 5.878

4.  Antimicrobial, antiproliferative and proapoptotic activities of extract, fractions and isolated compounds from the stem of Erythroxylum caatingae plowman.

Authors:  Jaciana S Aguiar; Rosilma O Araújo; Maria Do Desterro Rodrigues; Kêsia X F R Sena; André M Batista; Maria M P Guerra; Steno L Oliveira; Josean F Tavares; Marcelo S Silva; Silene C Nascimento; Teresinha Gonçalves Da Silva
Journal:  Int J Mol Sci       Date:  2012-03-29       Impact factor: 6.208

Review 5.  Research progress in the biological activities of 3,4,5-trimethoxycinnamic acid (TMCA) derivatives.

Authors:  Zefeng Zhao; Huanhuan Song; Jing Xie; Tian Liu; Xue Zhao; Xufei Chen; Xirui He; Shaoping Wu; Yongmin Zhang; Xiaohui Zheng
Journal:  Eur J Med Chem       Date:  2019-04-06       Impact factor: 6.514

Review 6.  Erythroxylum in Focus: An Interdisciplinary Review of an Overlooked Genus.

Authors:  David A Restrepo; Ernesto Saenz; Orlando Adolfo Jara-Muñoz; Iván F Calixto-Botía; Sioly Rodríguez-Suárez; Pablo Zuleta; Benjamin G Chavez; Juan A Sanchez; John C D'Auria
Journal:  Molecules       Date:  2019-10-21       Impact factor: 4.411
  6 in total

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