Literature DB >> 7921192

Preparative separation of components of the color additive D&C Red No. 28 (phloxine B) by pH-zone-refining counter-current chromatography.

A Weisz1, D Andrzejewski, Y Ito.   

Abstract

A pH-zone-refining counter-current chromatographic method was developed for the preparative (multigram) separation and purification of components of the commercial color additive D&C Red No. 28 (phloxine B). The chromatography of 3 and 6 g of color additive yielded 1.07 and 4.06 g, respectively, of pure 2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein, the principal component of D&C Red No. 28. The importance of the quantity of retainer acid (trifluoroacetic acid) relative to the amount of salt in the color additive is discussed.

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Year:  1994        PMID： 7921192     DOI： 10.1016/0021-9673(94)87076-4

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  5 in total

1.  Preparation of two novel monobrominated 2-(2',4'-dihydroxybenzoyl)-3,4,5,6-tetrachlorobenzoic acids and their separation from crude synthetic mixtures using vortex counter-current chromatography.

Authors:  Adrian Weisz; Jacob J Witten; Yun Zeng; Eugene P Mazzola; Yoichiro Ito
Journal:  J Chromatogr A       Date:  2012-03-19       Impact factor: 4.759

2.  Tropane aromatic ester alkaloids from a large-scale re-collection of Erythroxylum pervillei stem bark obtained in Madagascar.

Authors:  Young-Won Chin; William P Jones; Timothy J Waybright; Thomas G McCloud; Philippe Rasoanaivo; Gordon M Cragg; John M Cassady; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2006-03       Impact factor: 4.050

3.  Preparative separation and identification of novel subsidiary colors of the color additive D&C Red No. 33 (Acid Red 33) using spiral high-speed counter-current chromatography.

Authors:  Adrian Weisz; Clark D Ridge; Eugene P Mazzola; Yoichiro Ito
Journal:  J Chromatogr A       Date:  2015-01-03       Impact factor: 4.759

4.  Preparative separation of six rhynchophylla alkaloids from Uncaria macrophylla wall by pH-zone refining counter-current chromatography.

Authors:  Qinghai Zhang; Changhu Lin; Wenjuan Duan; Xiao Wang; Aiqin Luo
Journal:  Molecules       Date:  2013-12-12       Impact factor: 4.411

5.  In vitro antibacterial activities of phloxine B and other halogenated fluoresceins against methicillin-resistant Staphylococcus aureus.

Authors:  Avraham Rasooly; Adrian Weisz
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191
  5 in total

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