Literature DB >> 16552209

Influence of preservation versus division of ilioinguinal, iliohypogastric, and genital nerves during open mesh herniorrhaphy: prospective multicentric study of chronic pain.

Sergio Alfieri1, Fabio Rotondi, Andrea Di Giorgio, Uberto Fumagalli, Antonio Salzano, Dario Di Miceli, Marco Pericoli Ridolfini, Antonio Sgagari, Giovannibattista Doglietto.   

Abstract

OBJECTIVE: To evaluate whether the various surgical treatment reserved for ilioinguinal, iliohypogastric, and genital branch of the genitofemoral nerves, during open hernia mesh repair, is effective in reducing chronic postoperative pain.
BACKGROUND: Interest in chronic groin pain following herniorrhaphy has escalated, in recent years, due both to treatment and legal implications. However, much debate still exists concerning which treatment to reserve for the 3 inguinal sensory nerves.
METHODS: A multicentric prospective study involving 11 Italian institutions led to the recruitment of 973 cases of hernioplasty. All surgeons were asked to report whether or not each nerve had been identified and preserved or divided. The main endpoint of the study was the evaluation of moderate to severe chronic pain at 6 months and 1 year.
RESULTS: Overall, the presence of groin pain at the 6-month and 1-year follow-up was 9.7% and 4.1%, respectively. Pain was mild in 7.9% and moderate to severe in 2.1%, at 6 months, and mild in 3.6% and moderate to severe in 0.5%, at 1 year. Univariate and multivariate analysis showed that lack of identification of nerves is significantly correlated with presence of chronic pain, the risk of developing inguinal pain increasing with the number of nerves not detected. Likewise, division of nerves was clearly correlated with presence of chronic pain.
CONCLUSIONS: The present findings indicate that identification and preservation of nerves during open inguinal hernia repair reduce chronic incapacitating groin pain and that, in the majority of patients with chronic pain at 6 months, the pain at 1 year is resolved only with conservative or medical treatment.

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Year:  2006        PMID: 16552209      PMCID: PMC1448978          DOI: 10.1097/01.sla.0000208435.40970.00

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  36 in total

Review 1.  Postherniorrhaphy pain.

Authors:  T Callesen; H Kehlet
Journal:  Anesthesiology       Date:  1997-11       Impact factor: 7.892

2.  Retroperitoneal endoscopic neurectomy for nerve entrapment after hernia repair.

Authors:  L Krähenbühl; H Striffeler; H U Baer; M W Büchler
Journal:  Br J Surg       Date:  1997-02       Impact factor: 6.939

3.  Comparison of conventional anterior surgery and laparoscopic surgery for inguinal-hernia repair.

Authors:  M S Liem; Y van der Graaf; C J van Steensel; R U Boelhouwer; G J Clevers; W S Meijer; L P Stassen; J P Vente; W F Weidema; A J Schrijvers; T J van Vroonhoven
Journal:  N Engl J Med       Date:  1997-05-29       Impact factor: 91.245

4.  Three thousand one hundred seventy-five primary inguinal hernia repairs: advantages of ambulatory open mesh repair using local anesthesia.

Authors:  A E Kark; M N Kurzer; P A Belsham
Journal:  J Am Coll Surg       Date:  1998-04       Impact factor: 6.113

5.  Cooperative hernia study. Pain in the postrepair patient.

Authors:  J Cunningham; W J Temple; P Mitchell; J A Nixon; R M Preshaw; N A Hagen
Journal:  Ann Surg       Date:  1996-11       Impact factor: 12.969

6.  The mesh plug technique for recurrent groin herniorrhaphy: a nine-year experience of 407 repairs.

Authors:  I M Rutkow; A W Robbins
Journal:  Surgery       Date:  1998-11       Impact factor: 3.982

7.  Peripheral nerve injuries resulting from common surgical procedures in the lower portion of the abdomen.

Authors:  P Stulz; K M Pfeiffer
Journal:  Arch Surg       Date:  1982-03

8.  Mesh inguinodynia: a new clinical syndrome after inguinal herniorrhaphy?

Authors:  C P Heise; J R Starling
Journal:  J Am Coll Surg       Date:  1998-11       Impact factor: 6.113

9.  Bassini repair compared with laparoscopic repair for primary inguinal hernia: a randomised controlled trial.

Authors:  C D Dirksen; G L Beets; P M Go; F E Geisler; C G Baeten; G Kootstra
Journal:  Eur J Surg       Date:  1998-06

10.  Classification of chronic pain. Descriptions of chronic pain syndromes and definitions of pain terms. Prepared by the International Association for the Study of Pain, Subcommittee on Taxonomy.

Authors: 
Journal:  Pain Suppl       Date:  1986
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  50 in total

1.  Randomised clinical trial: conventional Lichtenstein vs. hernioplasty with self-adhesive mesh in bilateral inguinal hernia surgery.

Authors:  Jose L Porrero; María J Castillo; Ana Pérez-Zapata; María T Alonso; Oscar Cano-Valderrama; Esther Quirós; Sol Villar; Beatriz Ramos; Carlos Sánchez-Cabezudo; Oscar Bonachia; Alberto Marcos; Brígido Pérez
Journal:  Hernia       Date:  2014-11-04       Impact factor: 4.739

2.  Randomized controlled multicenter international clinical trial of self-gripping Parietex™ ProGrip™ polyester mesh versus lightweight polypropylene mesh in open inguinal hernia repair: interim results at 3 months.

Authors:  A Kingsnorth; M Gingell-Littlejohn; S Nienhuijs; S Schüle; P Appel; P Ziprin; A Eklund; M Miserez; S Smeds
Journal:  Hernia       Date:  2012-03-28       Impact factor: 4.739

3.  Sutureless hernioplasty with light-weight mesh and fibrin glue versus Lichtenstein procedure: a comparison of outcomes focusing on chronic postoperative pain.

Authors:  R Lionetti; B Neola; S Dilillo; D Bruzzese; G P Ferulano
Journal:  Hernia       Date:  2011-08-11       Impact factor: 4.739

Review 4.  Preservation versus division of ilioinguinal nerve on open mesh repair of inguinal hernia: a meta-analysis of randomized controlled trials.

Authors:  Wayne Hsu; Ching-Shyang Chen; Hung-Chia Lee; Hung-Hua Liang; Li-Jen Kuo; Po-Li Wei; Ka-Wai Tam
Journal:  World J Surg       Date:  2012-10       Impact factor: 3.352

5.  Chronified Pain Following Operative Procedures.

Authors:  Dominik Geil; Claudia Thomas; Annette Zimmer; Winfried Meissner
Journal:  Dtsch Arztebl Int       Date:  2019-04-12       Impact factor: 5.594

6.  Surgical techniques preventing chronic pain after Lichtenstein hernia repair: state-of-the-art vs daily practice in the Netherlands.

Authors:  A R Wijsmuller; J F M Lange; D van Geldere; M P Simons; G J Kleinrensink; W C J Hop; J Jeekel; J F Lange
Journal:  Hernia       Date:  2006-12-14       Impact factor: 4.739

Review 7.  Improving outcomes in hernia repair by the use of light meshes--a comparison of different implant constructions based on a critical appraisal of the literature.

Authors:  Dirk Weyhe; Orlin Belyaev; Christophe Müller; Kirsten Meurer; Karl-Heinz Bauer; Georgios Papapostolou; Waldemar Uhl
Journal:  World J Surg       Date:  2007-01       Impact factor: 3.352

8.  Prophylactic ilioinguinal neurectomy in open inguinal hernia repair.

Authors:  Sergio Alfieri; Davio Di Miceli; Giovanni Battista Doglietto
Journal:  Ann Surg       Date:  2007-04       Impact factor: 12.969

9.  Neuropathy after herniorrhaphy: indication for surgical treatment and outcome.

Authors:  Henri Vuilleumier; Martin Hübner; Nicolas Demartines
Journal:  World J Surg       Date:  2009-04       Impact factor: 3.352

10.  Pulsed radiofrequency for the treatment of chronic ilioinguinal neuropathy.

Authors:  Raj Mitra; Afshin Zeighami; Sean Mackey
Journal:  Hernia       Date:  2007-02-02       Impact factor: 4.739

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