Literature DB >> 16551419

Audit on the efficient use of cross-matched blood in elective total hip and total knee replacement.

B A Rogers1, D J Johnstone.   

Abstract

INTRODUCTION: This prospective audit studies the use of cross-matched blood in 301 patients over a 1-year period undergoing total knee (TKR) and total hip replacement (THR) surgery in an orthopaedic unit. PATIENTS AND METHODS: Analysis over the first 6 months revealed a high level of unnecessary cross-matched blood. The following interventions were introduced: (i) to cease routine cross-matching for THR; (ii) all patients to have a check full blood count on day 2 after surgery; and (iii) Hb < 8 g/dl to be considered as the trigger for transfusion in patients over 65 years and free from significant co-morbidity. These changes are in accordance with published national guidelines [Anon. Guidelines for the clinical use of red cell transfusions. Br J Haematol 2001; 113: 24-31].
RESULTS: In the next 6 months, the number of units cross-matched but not transfused fell by 96% for THR, and the cross-match transfusion (C:T) ratio reduced from 3.21 to 1.62. Reductions were also observed for the TKR cohort. These results provide evidence of a substantial risk and cost benefit in the use of this limited resource. A telephone survey of 44 hospitals revealed that 20 hospitals routinely cross-matched blood for THR and 11 do so for TKR.
CONCLUSIONS: Changes can be made to the Maximum Surgical Blood Ordering Schedules (MSBOS) in other orthopaedic units according to national guidelines.

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Year:  2006        PMID: 16551419      PMCID: PMC1964061          DOI: 10.1308/003588406X82952

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  7 in total

1.  Guidelines for the clinical use of red cell transfusions.

Authors:  M F Murphy; T B Wallington; P Kelsey; F Boulton; M Bruce; H Cohen; J Duguid; S M Knowles; G Poole; L M Williamson
Journal:  Br J Haematol       Date:  2001-04       Impact factor: 6.998

Review 2.  New variant Creutzfeldt-Jakob disease (nvCJD): the risk of transmission by blood transfusion and the potential benefit of leukocyte-reduction of blood components.

Authors:  M F Murphy
Journal:  Transfus Med Rev       Date:  1999-04

Review 3.  Transfusion medicine. Second of two parts--blood conservation.

Authors:  L T Goodnough; M E Brecher; M H Kanter; J P AuBuchon
Journal:  N Engl J Med       Date:  1999-02-18       Impact factor: 91.245

4.  An analysis of blood management in patients having a total hip or knee arthroplasty.

Authors:  B E Bierbaum; J J Callaghan; J O Galante; H E Rubash; R E Tooms; R B Welch
Journal:  J Bone Joint Surg Am       Date:  1999-01       Impact factor: 5.284

5.  Serious hazards of transfusion (SHOT) initiative: analysis of the first two annual reports.

Authors:  L M Williamson; S Lowe; E M Love; H Cohen; K Soldan; D B McClelland; P Skacel; J A Barbara
Journal:  BMJ       Date:  1999-07-03

6.  A safe, simple and cost-effective protocol for blood transfusion in primary total knee replacement.

Authors:  A Mehra; J Murray; C deAlwis
Journal:  Ann R Coll Surg Engl       Date:  2004-07       Impact factor: 1.891

7.  Use of blood products for elective surgery in 43 European hospitals. The Sanguis Study Group.

Authors: 
Journal:  Transfus Med       Date:  1994-12       Impact factor: 2.019

  7 in total
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1.  Comparing the efficacy of intravenous or intra-articular tranexamic acid in reducing blood loss in simultaneous bilateral knee replacement surgery without the use of tourniquet.

Authors:  Mridul Arora; Saurabh Singh; Varun Gupta; Ashutosh Dongre; Vijay Shetty
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-03-29

2.  A study of pre-operative type and screen in breast surgery: improved efficiency and cost saving.

Authors:  R S Prichard; M O'Keefe; R McLaughlin; C Malone; K J Sweeney; M J Kerin
Journal:  Ir J Med Sci       Date:  2011-01-01       Impact factor: 1.568

3.  Blood utilization in orthopedic and trauma practice.

Authors:  Bader Kamal Tayara; Moaad Hatim Al-Faraidy; Faisal Abdullah Al-Sayel; Abdallah S Al-Omran; Mir Sadat-Ali
Journal:  Int J Appl Basic Med Res       Date:  2015 May-Aug
  3 in total

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