Mridul Arora1, Saurabh Singh2, Varun Gupta1, Ashutosh Dongre1, Vijay Shetty1. 1. Hiranandani Orthopaedic Medical Education (HOME), Dr L H Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, 400076, India. 2. Hiranandani Orthopaedic Medical Education (HOME), Dr L H Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, 400076, India. drsaurabhsingh14@gmail.com.
Abstract
PURPOSE: To compare the effect of intravenous or intra-articular route of administration of tranexamic acid in reducing the blood loss in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquets. METHODS: Prospective cohort study of 30 consecutive patients grouped into two groups; Group 1: intravenous group and group 2: intra-articular group. Two outcome measures were studied; mean drop in post-operative haemoglobin and need for blood transfusion in both groups. RESULTS: No significant difference in mean drop of haemoglobin and need for blood transfusion in both groups. CONCLUSION: Route of administration of tranexamic acid does not influence on the mean drop of haemoglobin and need for blood transfusion in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquet.
PURPOSE: To compare the effect of intravenous or intra-articular route of administration of tranexamic acid in reducing the blood loss in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquets. METHODS: Prospective cohort study of 30 consecutive patients grouped into two groups; Group 1: intravenous group and group 2: intra-articular group. Two outcome measures were studied; mean drop in post-operative haemoglobin and need for blood transfusion in both groups. RESULTS: No significant difference in mean drop of haemoglobin and need for blood transfusion in both groups. CONCLUSION: Route of administration of tranexamic acid does not influence on the mean drop of haemoglobin and need for blood transfusion in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquet.
Entities:
Keywords:
Blood loss; Route of administration; Simultaneous bilateral total knee replacement; Tranexamic acid; Without tourniquet
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