Literature DB >> 16539891

An overview of the genetics of substance use disorders.

H M Lachman1.   

Abstract

Twin, family, and adoption studies show that genetic factors play a significant role in vulnerability to becoming addicted to drugs. Through a combination of genetic approaches, the variant alleles responsible for interindividual differences in susceptibility to addiction are being uncovered.

Mesh：

Substances：

Year:  2006        PMID： 16539891     DOI： 10.1007/s11920-006-0013-3

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN： 1523-3812            Impact factor:   5.285


  68 in total

1.  Insertion/deletion variant (-141C Ins/Del) in the 5' regulatory region of the dopamine D2 receptor gene: lack of association with schizophrenia and bipolar affective disorder. Short communication.

Authors:  G Stöber; S Jatzke; A Heils; G Jungkunz; M Knapp; R Mössner; P Riederer; K P Lesch
Journal:  J Neural Transm (Vienna)       Date:  1998       Impact factor: 3.575

2.  Genetic and environmental influences on drug use and abuse/dependence in male and female twins.

Authors:  M B van den Bree; E O Johnson; M C Neale; R W Pickens
Journal:  Drug Alcohol Depend       Date:  1998-11-01       Impact factor: 4.492

3.  Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study.

Authors:  R Horowitz; M Kotler; E Shufman; S Aharoni; I Kremer; H Cohen; R P Ebstein
Journal:  Am J Med Genet       Date:  2000-10-09

4.  Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia.

Authors:  Joel Gelernter; Carolien Panhuysen; Roger Weiss; Kathleen Brady; Victor Hesselbrock; Bruce Rounsaville; James Poling; Marsha Wilcox; Lindsay Farrer; Henry R Kranzler
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2005-07-05       Impact factor: 3.568

5.  The proenkephalin gene (PENK) and opioid dependence.

Authors:  D E Comings; H Blake; G Dietz; R Gade-Andavolu; R S Legro; G Saucier; P Johnson; R Verde; J P MacMurray
Journal:  Neuroreport       Date:  1999-04-06       Impact factor: 1.837

6.  Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms.

Authors:  G R Uhl; Q R Liu; D Walther; J Hess; D Naiman
Journal:  Am J Hum Genet       Date:  2001-11-06       Impact factor: 11.025

7.  Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.

Authors:  Joke Beuten; Jennie Z Ma; Thomas J Payne; Randolph T Dupont; Karen M Crews; Grant Somes; Nancy J Williams; Robert C Elston; Ming D Li
Journal:  Am J Hum Genet       Date:  2005-03-09       Impact factor: 11.025

8.  Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction.

Authors:  C Bond; K S LaForge; M Tian; D Melia; S Zhang; L Borg; J Gong; J Schluger; J A Strong; S M Leal; J A Tischfield; M J Kreek; L Yu
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205

Review 9.  Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence.

Authors:  P J Harrison; D R Weinberger
Journal:  Mol Psychiatry       Date:  2005-01       Impact factor: 15.992

10.  Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains.

Authors:  W H Berrettini; T N Ferraro; R C Alexander; A M Buchberg; W H Vogel
Journal:  Nat Genet       Date:  1994-05       Impact factor: 38.330
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  10 in total

1.  Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses.

Authors:  Huiping Zhang; Fan Wang; Henry R Kranzler; Raymond F Anton; Joel Gelernter
Journal:  Behav Brain Funct       Date:  2012-05-16       Impact factor: 3.759

2.  Evidence for a two-stage model of dependence using the NESARC and its implications for genetic association studies.

Authors:  Gary A Heiman; Elizabeth Ogburn; Prakash Gorroochurn; Katherine M Keyes; Deborah Hasin
Journal:  Drug Alcohol Depend       Date:  2007-10-22       Impact factor: 4.492

3.  Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction.

Authors:  Nermana Mehić-Basara; Lilijana Oruč; Lejla Kapur-Pojskić; Jasmin Ramić
Journal:  Bosn J Basic Med Sci       Date:  2013-08       Impact factor: 3.363

4.  The media and behavioral genetics: Alternatives coexisting with addiction genetics.

Authors:  Molly J Dingel; Jenny Ostergren; Jennifer B McCormick; Rachel Hammer; Barbara A Koenig
Journal:  Sci Technol Human Values       Date:  2015-07-01

Review 5.  The genetics of substance dependence.

Authors:  Jen-Chyong Wang; Manav Kapoor; Alison M Goate
Journal:  Annu Rev Genomics Hum Genet       Date:  2012-06-11       Impact factor: 8.929

6.  Substance use disorder genetic research: investigators and participants grapple with the ethical issues.

Authors:  Marilyn E Coors; Kristen M Raymond
Journal:  Psychiatr Genet       Date:  2009-04       Impact factor: 2.458

7.  Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats.

Authors:  Roberto Picetti; Jilda A Caccavo; Ann Ho; Mary Jeanne Kreek
Journal:  Psychopharmacology (Berl)       Date:  2011-09-06       Impact factor: 4.530

8.  Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.

Authors:  Falk W Lohoff; Andrew E Weller; Paul J Bloch; Aleksandra H Nall; Thomas N Ferraro; Kyle M Kampman; Helen M Pettinati; David W Oslin; Charles A Dackis; Charles P O'Brien; Wade H Berrettini
Journal:  Neuropsychopharmacology       Date:  2008-08-13       Impact factor: 7.853

9.  Patterns of co-morbidity of eating disorders and substance use in Swedish females.

Authors:  T L Root; E M Pisetsky; L Thornton; P Lichtenstein; N L Pedersen; C M Bulik
Journal:  Psychol Med       Date:  2009-04-20       Impact factor: 7.723

10.  Key future research questions on mediators and moderators of behaviour change processes for substance abuse.

Authors:  Jürgen Rehm
Journal:  Int J Methods Psychiatr Res       Date:  2008-06       Impact factor: 4.035
  10 in total

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