Literature DB >> 16518398

Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA.

Inés Li de la Sierra-Gallay1, Nathalie Mathy, Olivier Pellegrini, Ciarán Condon.   

Abstract

The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16518398     DOI： 10.1038/nsmb1066

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  25 in total

Review 1.  tRNA biology charges to the front.

Authors:  Eric M Phizicky; Anita K Hopper
Journal:  Genes Dev       Date:  2010-09-01       Impact factor: 11.361

2.  The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes.

Authors:  Ryohei Ishii; Asako Minagawa; Hiroaki Takaku; Masamichi Takagi; Masayuki Nashimoto; Shigeyuki Yokoyama
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-07-21

Review 3.  Protein factors in pre-mRNA 3'-end processing.

Authors:  C R Mandel; Y Bai; L Tong
Journal:  Cell Mol Life Sci       Date:  2008-04       Impact factor: 9.261

4.  Catalytic properties of RNase BN/RNase Z from Escherichia coli: RNase BN is both an exo- and endoribonuclease.

Authors:  Tanmay Dutta; Murray P Deutscher
Journal:  J Biol Chem       Date:  2009-04-14       Impact factor: 5.157

5.  Effect of changes in the flexible arm on tRNase Z processing kinetics.

Authors:  Louis Levinger; Angela Hopkinson; Rohini Desetty; Christopher Wilson
Journal:  J Biol Chem       Date:  2009-04-07       Impact factor: 5.157

6.  How a CCA sequence protects mature tRNAs and tRNA precursors from action of the processing enzyme RNase BN/RNase Z.

Authors:  Tanmay Dutta; Arun Malhotra; Murray P Deutscher
Journal:  J Biol Chem       Date:  2013-09-10       Impact factor: 5.157

7.  Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.

Authors:  Sakurako Goto-Ito; Takuhiro Ito; Mitsuo Kuratani; Yoshitaka Bessho; Shigeyuki Yokoyama
Journal:  Nat Struct Mol Biol       Date:  2009-09-13       Impact factor: 15.369

8.  Pathogenesis-related mutations in the T-loops of human mitochondrial tRNAs affect 3' end processing and tRNA structure.

Authors:  Louis Levinger; Dmitri Serjanov
Journal:  RNA Biol       Date:  2012-03-01       Impact factor: 4.652

9.  Identification and analysis of candidate fungal tRNA 3'-end processing endonucleases tRNase Zs, homologs of the putative prostate cancer susceptibility protein ELAC2.

Authors:  Wei Zhao; Haiyan Yu; Shuzhen Li; Ying Huang
Journal:  BMC Evol Biol       Date:  2010-09-06       Impact factor: 3.260

10.  RNase J1 endonuclease activity as a probe of RNA secondary structure.

Authors:  Roula Daou-Chabo; Ciarán Condon
Journal:  RNA       Date:  2009-05-20       Impact factor: 4.942
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.