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Literature DB >> 1650756

Assignment of the gene coding for human cytochrome c oxidase subunit VIb to chromosome 19, band q13.1, by fluorescence in situ hybridisation.

J W Taanman¹, A Y van der Veen, C Schrage, H de Vries, C H Buys.

Abstract

A cloned, 40 kb, genomic DNA fragment, containing the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking sequences, was used as a probe to localize the subunit VIb gene on human metaphase chromosomes. The probe was labelled with Bio-11-dUTP and detected by fluorescence. Subsequent R-banding indicated that the cytochrome c oxidase subunit VIb gene is localized in band 19q13.1, extending the evidence that the human nuclear genes of cytochrome c oxidase are not clustered.

Entities: Chemical Gene Species

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Year: 1991 PMID： 1650756 DOI： 10.1007/bf00200913

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

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