Literature DB >> 16466861

Risk factors for alcohol misuse: examining heart rate reactivity to alcohol, alcohol sensitivity, and personality constructs.

Lara A Ray1, John McGeary, Erin Marshall, Kent E Hutchison.   

Abstract

OBJECTIVE: Heart rate reactivity to alcohol has been conceptualized as an index of alcohol-induced reward and has been associated with a sensation seeking personality profile. The goal of this study is to expand on previous findings regarding the significance of heart rate reactivity to alcohol while examining convergent lines of research on alcohol sensitivity, the rewarding effects of alcohol, and personality constructs.
METHODS: Participants (N=47) were heavy drinkers who completed an intravenous alcohol challenge protocol.
RESULTS: Analyses revealed a significant negative relationship between heart rate reactivity and alcohol-induced sedation and subjective intoxication. Heart rate reactivity was positively related to self-reported alcohol-induced vigor and to impulsivity and sensation seeking scores.
CONCLUSIONS: Taken together, these results suggest that individuals with heightened heart rate reactivity to alcohol appear to be more sensitive to the invigorating properties of alcohol, while being less sensitive to the sedative and unpleasant effects of alcohol intoxication. These findings have implications to the conceptualization of heart rate reactivity to alcohol as a biobehavioral marker of alcohol sensitivity.

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Year:  2006        PMID: 16466861     DOI: 10.1016/j.addbeh.2006.01.010

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


  19 in total

1.  Cardiac reactivity during the ascending phase of acute intravenous alcohol exposure and association with subjective perceptions of intoxication in social drinkers.

Authors:  Vatsalya Vatsalya; Reza Momenan; Daniel W Hommer; Vijay A Ramchandani
Journal:  Alcohol Clin Exp Res       Date:  2014-03-21       Impact factor: 3.455

Review 2.  Human and laboratory rodent low response to alcohol: is better consilience possible?

Authors:  John C Crabbe; Richard L Bell; Cindy L Ehlers
Journal:  Addict Biol       Date:  2010-04       Impact factor: 4.280

3.  Acute subjective response to alcohol as a function of reward and punishment sensitivity.

Authors:  David H Morris; Hayley Treloar; Chia-Lin Tsai; Kayleigh N McCarty; Denis M McCarthy
Journal:  Addict Behav       Date:  2016-03-29       Impact factor: 3.913

Review 4.  Subjective responses to alcohol consumption as endophenotypes: advancing behavioral genetics in etiological and treatment models of alcoholism.

Authors:  Lara A Ray; James Mackillop; Peter M Monti
Journal:  Subst Use Misuse       Date:  2010-09       Impact factor: 2.164

5.  Sensation seeking in long-term abstinent alcoholics, treatment-naïve active alcoholics, and nonalcoholic controls.

Authors:  George Fein; Victoria Di Sclafani; Peter Finn
Journal:  Alcohol Clin Exp Res       Date:  2010-04-05       Impact factor: 3.455

Review 6.  Sensitivity to ethanol and other hedonic stimuli in an animal model of adolescence: implications for prevention science?

Authors:  Linda Patia Spear; Elena I Varlinskaya
Journal:  Dev Psychobiol       Date:  2010-04       Impact factor: 3.038

7.  The amphetamine response moderates the relationship between negative emotionality and alcohol use.

Authors:  Kenneth J D Allen; Frances H Gabbay
Journal:  Alcohol Clin Exp Res       Date:  2012-12-14       Impact factor: 3.455

8.  Catching the alcohol buzz: an examination of the latent factor structure of subjective intoxication.

Authors:  Lara A Ray; James MacKillop; Adam Leventhal; Kent E Hutchison
Journal:  Alcohol Clin Exp Res       Date:  2009-09-17       Impact factor: 3.455

9.  Female drinkers are more sensitive than male drinkers to alcohol-induced heart rate increase.

Authors:  Roberto U Cofresí; Bruce D Bartholow; Kim Fromme
Journal:  Exp Clin Psychopharmacol       Date:  2019-12-02       Impact factor: 3.157

10.  Behavioral inhibition and activation systems: differences in substance use expectancy organization and activation in memory.

Authors:  Jeffrey S Simons; Robert D Dvorak; Cathy Lau-Barraco
Journal:  Psychol Addict Behav       Date:  2009-06
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