Literature DB >> 20374208

Sensation seeking in long-term abstinent alcoholics, treatment-naïve active alcoholics, and nonalcoholic controls.

George Fein1, Victoria Di Sclafani, Peter Finn.   

Abstract

BACKGROUND: Elevated sensation seeking is associated with the development of alcohol dependence; however, it has not been studied in long-term abstinent alcoholics. In the current study, we examine sensation seeking in middle-aged long-term abstinent alcoholics (LTAA) and in younger actively drinking treatment-naïve alcoholics (TxN).
METHODS: A modified version of the Sensation Seeking Scale (SSS) was administered to 52 middle-aged LTAA (average age = 46.6 years) and 86 younger TxN (average age = 31.2 years), each study with its own age and gender comparable nonalcoholic controls (NAC). The SSS was modified to remove items specifically associated with alcohol or drug use. The associations between the SSS and alcohol use and deviance proneness were examined.
RESULTS: The 2 NAC samples did not differ on the SSS, allowing the 2 NAC samples to be combined into a single control group (NAC = 118), and the LTAA and TxN samples to be directly compared without concern for cohort effects. LTAA did not differ from NAC on the SSS; however, the TxN group had higher SSS scores compared with NAC on all subscales except Boredom Susceptibility. Sensation seeking was comparably associated with lower socialization in each group.
CONCLUSIONS: The results suggest that either sensation seeking normalizes with long-term abstinence or that relatively normal levels of sensation seeking predict the ability to achieve long-term abstinence. In either case, the results have important implications for our understanding of long-term abstinence.

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Mesh:

Year:  2010        PMID: 20374208      PMCID: PMC3246427          DOI: 10.1111/j.1530-0277.2010.01179.x

Source DB:  PubMed          Journal:  Alcohol Clin Exp Res        ISSN: 0145-6008            Impact factor:   3.455


  33 in total

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  9 in total

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Journal:  Neuropsychology       Date:  2016-01-11       Impact factor: 3.295

2.  Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene.

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3.  Event-related potentials during visual target detection in treatment-naïve active alcoholics.

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Journal:  Alcohol Clin Exp Res       Date:  2018-07-05       Impact factor: 3.455

5.  Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands.

Authors:  Vivia V McCutcheon; Marc A Schuckit; John R Kramer; Grace Chan; Howard J Edenberg; Tom L Smith; Annah K Bender; Victor Hesselbrock; Michie Hesselbrock; Kathleen K Bucholz
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Review 6.  Contributions of studies on alcohol use disorders to understanding cerebellar function.

Authors:  Natalie M Zahr; Anne-Lise Pitel; Sandra Chanraud; Edith V Sullivan
Journal:  Neuropsychol Rev       Date:  2010-09-01       Impact factor: 7.444

Review 7.  Neuroimmune basis of alcoholic brain damage.

Authors:  Fulton T Crews; Ryan P Vetreno
Journal:  Int Rev Neurobiol       Date:  2014       Impact factor: 3.230

8.  "Cognitive, emotion control, and motor performance of adolescents in the NCANDA study: Contributions from alcohol consumption, age, sex, ethnicity, and family history of addiction": Correction to Sullivan et al. (2016).

Authors: 
Journal:  Neuropsychology       Date:  2016-08-08       Impact factor: 3.295

9.  Altered Cerebro-Cerebellar Dynamic Functional Connectivity in Alcohol Use Disorder: a Resting-State fMRI Study.

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  9 in total

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