Literature DB >> 16460766

Applications of LC-MS in the study of the uptake, distribution, metabolism and excretion of bioactive polyphenols from dietary supplements.

Stephen Barnes1, Jeevan K Prasain, Chao-Cheng Wang, D Ray Moore.   

Abstract

Specific and quantitative analyses of the bioactive components and their metabolites in body fluids are essential to assess the interaction between groups of compounds in dietary supplements and preparations of psychoactives. Reverse-phase LC separations combined with tandem mass spectrometry provide the necessary specificity and sensitivity. In this paper, applications of these methods are described for the analysis of isoflavones, salvinorin A, synephrine isomers and their metabolites in serum, urine and aqueous humor.

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Year:  2006        PMID: 16460766     DOI: 10.1016/j.lfs.2005.12.002

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  10 in total

Review 1.  Silybin and the liver: from basic research to clinical practice.

Authors:  Carmela Loguercio; Davide Festi
Journal:  World J Gastroenterol       Date:  2011-05-14       Impact factor: 5.742

2.  Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat.

Authors:  Kyle A Floyd; David R Stella; Chao-Cheng Wang; Sara Laurentz; George P McCabe; Om P Srivastava; Stephen Barnes
Journal:  Exp Eye Res       Date:  2010-12-10       Impact factor: 3.467

Review 3.  Botanicals for age-related diseases: from field to practice.

Authors:  Connie M Weaver; Stephen Barnes; J Michael Wyss; Helen Kim; Dorothy M Morré; D James Morré; James E Simon; Mary Ann Lila; Elsa M Janle; Mario G Ferruzzi
Journal:  Am J Clin Nutr       Date:  2008-02       Impact factor: 7.045

Review 4.  Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers.

Authors:  Stephen Barnes; Diane F Birt; Barrie R Cassileth; William T Cefalu; Floyd H Chilton; Norman R Farnsworth; Ilya Raskin; Richard B van Breemen; Connie M Weaver
Journal:  Am J Clin Nutr       Date:  2008-02       Impact factor: 7.045

5.  Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor.

Authors:  Feng Yan; Ruslan V Bikbulatov; Viorel Mocanu; Nedyalka Dicheva; Carol E Parker; William C Wetsel; Philip D Mosier; Richard B Westkaemper; John A Allen; Jordan K Zjawiony; Bryan L Roth
Journal:  Biochemistry       Date:  2009-07-28       Impact factor: 3.162

Review 6.  Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A.

Authors:  Christopher W Cunningham; Richard B Rothman; Thomas E Prisinzano
Journal:  Pharmacol Rev       Date:  2011-03-28       Impact factor: 25.468

7.  Improved high sensitivity analysis of polyphenols and their metabolites by nano-liquid chromatography-mass spectrometry.

Authors:  Landon Wilson; Ali Arabshahi; Brigitte Simons; Jeevan K Prasain; Stephen Barnes
Journal:  Arch Biochem Biophys       Date:  2014-06-23       Impact factor: 4.013

8.  Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.

Authors:  R Capasso; F Borrelli; M G Cascio; G Aviello; K Huben; J K Zjawiony; P Marini; B Romano; V Di Marzo; F Capasso; A A Izzo
Journal:  Br J Pharmacol       Date:  2008-07-14       Impact factor: 8.739

9.  Research Highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases.

Authors:  Connie M Weaver; Stephen Barnes; J Michael Wyss; Helen Kim; Dorothy M Morré; D James Morré; James E Simon; Mary Ann Lila; Elsa M Janle; Mario G Ferruzzi
Journal:  Pharm Biol       Date:  2009-08-01       Impact factor: 3.503

10.  Current literature in mass spectrometry.

Authors: 
Journal:  J Mass Spectrom       Date:  2007-01       Impact factor: 1.982

  10 in total

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