Literature DB >> 1645287

Stoichiometry of metal-tetracycline/H+ antiport mediated by transposon Tn10-encoded tetracycline resistance protein in Escherichia coli.

A Yamaguchi1, Y Iwasaki-Ohba, N Ono, M Kaneko-Ohdera, T Sawai.   

Abstract

The tetracycline resistance protein (TetA) endoded by transposon Tn10 mediates the efflux of divalent cation-tetracycline chelating complexes [Yamaguchi, A., Udagawa, T. and Sawai, T. (1990) J. Biol. Chem. 265, 4809-4813]. It was confirmed that protons were antiported with the complexes through an electrically-neutral process because the antiport consumed delta pH but not delta psi. The quantitative relationship between delta pH and delta pTC determined by a flow-dialysis method clearly indicated a 1:1 stoichiometry of the monocationic metal-tetracycline/H+ exchange.

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Year:  1991        PMID： 1645287     DOI： 10.1016/0014-5793(91)80527-a

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  20 in total

1.  Decreased function of the class B tetracycline efflux protein Tet with mutations at aspartate 15, a putative intramembrane residue.

Authors:  L M McMurry; M Stephan; S B Levy
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

2.  Cloning, sequencing and analysis of the pucC genes from Rubrivivax gelatinosus strain 151 and Rhodopseudomonas acidophila strain 10050.

Authors:  A E Simmons; S J Barrett; C N Hunter; R J Cogdell
Journal:  Photosynth Res       Date:  2000       Impact factor: 3.573

3.  Reduction of acid tolerance by tetracycline in Escherichia coli expressing tetA(C) is reversed by cations.

Authors:  Kai F Hung; Jeffrey J Byrd; Jeffrey L Bose; Charles W Kaspar
Journal:  Appl Environ Microbiol       Date:  2006-06       Impact factor: 4.792

4.  Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate.

Authors:  Frédéric M Sapunaric; Stuart B Levy
Journal:  Antimicrob Agents Chemother       Date:  2007-05-21       Impact factor: 5.191

5.  A novel major facilitator superfamily protein at the tonoplast influences zinc tolerance and accumulation in Arabidopsis.

Authors:  Michael J Haydon; Christopher S Cobbett
Journal:  Plant Physiol       Date:  2007-02-02       Impact factor: 8.340

Review 6.  rRNA Binding Sites and the Molecular Mechanism of Action of the Tetracyclines.

Authors:  Chinwe U Chukwudi
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

7.  Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux.

Authors:  R M Kennan; L M McMurry; S B Levy; J I Rood
Journal:  J Bacteriol       Date:  1997-11       Impact factor: 3.490

8.  The purified Bacillus subtilis tetracycline efflux protein TetA(L) reconstitutes both tetracycline-cobalt/H+ and Na+(K+)/H+ exchange.

Authors:  J Cheng; D B Hicks; T A Krulwich
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

9.  Mutations in the tetA(B) gene that cause a change in substrate specificity of the tetracycline efflux pump.

Authors:  G G Guay; M Tuckman; D M Rothstein
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

10.  A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter.

Authors:  Y Someya; A Yamaguchi; T Sawai
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191
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