Literature DB >> 16446843

Isoindoles and dihydroisoquinolines by gold-catalyzed intramolecular hydroamination of alkynes.

Daniel Kadzimirsz1, Dirk Hildebrandt, Klaus Merz, Gerald Dyker.   

Abstract

The title compounds are enantioselectively synthesized in just two preparative steps, making use of the Ugi-four-component reaction with an amino acid as chiral component, followed by a gold-catalyzed hydroamination.

Entities:  

Year:  2006        PMID： 16446843     DOI： 10.1039/b516017k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  One-pot multicomponent synthesis of two novel thiolactone scaffolds.

Authors:  B Beck; S Srivastava; K Khoury; E Herdtweck; Alexander Dömling
Journal:  Mol Divers       Date:  2010-04-21       Impact factor: 2.943

2.  Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines: application in the construction of the communesin ring system.

Authors:  Seth L Crawley; Raymond L Funk
Journal:  Org Lett       Date:  2006-08-31       Impact factor: 6.005

3.  Efficient assembly of iminodicarboxamides by a "truly" four-component reaction.

Authors:  Kareem Khoury; Mantosh K Sinha; Tadamichi Nagashima; Eberhardt Herdtweck; Alexander Dömling
Journal:  Angew Chem Int Ed Engl       Date:  2012-09-11       Impact factor: 15.336

4.  Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine.

Authors:  Nicholas R Perl; Nathan D Ide; Sudeep Prajapati; Hahdi H Perfect; Sergio G Durón; David Y Gin
Journal:  J Am Chem Soc       Date:  2010-02-17       Impact factor: 15.419
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.