Literature DB >> 16444785

Artemisone--a highly active antimalarial drug of the artemisinin class.

Richard K Haynes1, Burkhard Fugmann, Jörg Stetter, Karl Rieckmann, Hans-Dietrich Heilmann, Ho-Wai Chan, Man-Ki Cheung, Wai-Lun Lam, Ho-Ning Wong, Simon L Croft, Livia Vivas, Lauren Rattray, Lindsay Stewart, Wallace Peters, Brian L Robinson, Michael D Edstein, Barbara Kotecka, Dennis E Kyle, Bernhard Beckermann, Michael Gerisch, Martin Radtke, Gabriele Schmuck, Wolfram Steinke, Ute Wollborn, Karl Schmeer, Axel Römer.   

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Year:  2006        PMID： 16444785     DOI： 10.1002/anie.200503071

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  58 in total

1.  Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.

Authors:  Rachel D Slack; Bryan T Mott; Lauren E Woodard; Abhai Tripathi; Abhai Triphati; David Sullivan; Elizabeth Nenortas; Sonya C T Girdwood; Theresa A Shapiro; Gary H Posner
Journal:  J Med Chem       Date:  2011-12-15       Impact factor: 7.446

2.  Evaluation of the 2-Aminomethylphenol JPC-2997 in Aotus Monkeys Infected with Plasmodium falciparum.

Authors:  Fiona McCallum; Ivor Harris; Karin van Breda; Sai Lata De; Danielle I Stanisic; Michael F Good; David P Jacobus; Michael D Edstein
Journal:  Antimicrob Agents Chemother       Date:  2015-12-14       Impact factor: 5.191

3.  Synthesis of artemiside and its effects in combination with conventional drugs against severe murine malaria.

Authors:  Jin Guo; Armand W Guiguemde; Annael Bentura-Marciano; Julie Clark; Richard K Haynes; Wing-Chi Chan; Ho-Ning Wong; Nicholas H Hunt; R Kiplin Guy; Jacob Golenser
Journal:  Antimicrob Agents Chemother       Date:  2011-10-17       Impact factor: 5.191

4.  Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growth.

Authors:  Yuliya V Mishina; Sanjeev Krishna; Richard K Haynes; John C Meade
Journal:  Antimicrob Agents Chemother       Date:  2007-03-05       Impact factor: 5.191

5.  Microbiology: Malaria runs rings round artemisinin.

Authors:  Jeremy Burrows
Journal:  Nature       Date:  2015-04-15       Impact factor: 49.962

6.  Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates.

Authors:  Jennifer R Mazzone; Ryan C Conyers; Abhai K Tripathi; David J Sullivan; Gary H Posner
Journal:  Bioorg Med Chem Lett       Date:  2014-04-16       Impact factor: 2.823

7.  Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters.

Authors:  Ryan C Conyers; Jennifer R Mazzone; Abhai K Tripathi; David J Sullivan; Gary H Posner
Journal:  Bioorg Med Chem Lett       Date:  2014-11-27       Impact factor: 2.823

8.  Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs.

Authors:  Bryan T Mott; Abhai Tripathi; Maxime A Siegler; Cathy D Moore; David J Sullivan; Gary H Posner
Journal:  J Med Chem       Date:  2013-03-07       Impact factor: 7.446

9.  Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.

Authors:  Andrew S Rosenthal; Xiaochun Chen; Jun O Liu; Diana C West; Paul J Hergenrother; Theresa A Shapiro; Gary H Posner
Journal:  J Med Chem       Date:  2009-02-26       Impact factor: 7.446

Review 10.  Artemisinins: their growing importance in medicine.

Authors:  Sanjeev Krishna; Leyla Bustamante; Richard K Haynes; Henry M Staines
Journal:  Trends Pharmacol Sci       Date:  2008-08-25       Impact factor: 14.819
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