| Literature DB >> 16413919 |
Ana M Gamero1, Joost J Oppenheim.
Abstract
Both interleukin-1 receptor (IL-1R) and toll-like receptor 2 (TLR2) signal via the adapter molecule MyD88. However, in response to a cutaneous infection challenge, the downstream signaling events diverge and IL-1R, but not TLR2, proves to be essential for host defense.Entities:
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Year: 2006 PMID: 16413919 DOI: 10.1016/j.immuni.2005.12.007
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745