| Literature DB >> 18036805 |
Florence Allantaz1, Damien Chaussabel, Jacques Banchereau, Virginia Pascual.
Abstract
Interleukin 1b (IL-1b) is emerging as mediator of a wide range of human diseases. Availability of IL-1 blockers that result in clinical benefits to patients with these diseases is creating a demand for biomarkers to diagnose as well as to predict and follow responses to therapy. Blood gene expression profiling can be used to identify such biomarkers. This review will summarize recent studies in the field and will discuss some of the challenges raised by the use of this technology in biomarker discovery.Entities:
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Year: 2007 PMID: 18036805 PMCID: PMC2747489 DOI: 10.1016/j.coi.2007.10.003
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486