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Literature DB >> 16391750

A synthetic, chloride-selective channel that alters chloride transport in epithelial cells.

Robert Pajewski¹, Raquel Garcia-Medina, Steven L Brody, W Matthew Leevy, Paul H Schlesinger, George W Gokel.

Abstract

An Ussing chamber was used to demonstrate that synthetic amphiphilic anion transporters function as chloride transporters in mammalian airway epithelial cells.

Entities: Chemical Species

Mesh：

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Year: 2005 PMID： 16391750 PMCID： PMC2711530 DOI： 10.1039/b513940f

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

16 in total

1. pH-regulated chloride secretion in fetal lung epithelia.

Authors: C J Blaisdell; R D Edmonds; X T Wang; S Guggino; P L Zeitlin
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2000-06 Impact factor: 5.464

2. Anchor chain length alters the apparent mechanism of chloride channel function in SCMTR derivatives.

Authors: Paul H Schlesinger; Natasha K Djedovic; Riccardo Ferdani; Jolanta Pajewska; Robert Pajewski; George W Gokel
Journal: Chem Commun (Camb) Date: 2003-02-07 Impact factor: 6.222

3. Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.

Authors: Yingjian You; Edward J Richer; Tao Huang; Steven L Brody
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2002-08-09 Impact factor: 5.464

Review 4. The epithelial sodium channel: from molecule to disease.

Authors: L Schild
Journal: Rev Physiol Biochem Pharmacol Date: 2004-05-14 Impact factor: 5.545

5. Regulation of sodium absorption by canine tracheal epithelium.

Authors: J J Cullen; M J Welsh
Journal: J Clin Invest Date: 1987-01 Impact factor: 14.808

6. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits.

Authors: C M Canessa; L Schild; G Buell; B Thorens; I Gautschi; J D Horisberger; B C Rossier
Journal: Nature Date: 1994-02-03 Impact factor: 49.962

7. Evidence for dimer formation by an amphiphilic heptapeptide that mediates chloride and carboxyfluorescein release from liposomes.

Authors: Robert Pajewski; Riccardo Ferdani; Jolanta Pajewska; Natasha Djedovic; Paul H Schlesinger; George W Gokel
Journal: Org Biomol Chem Date: 2005-01-13 Impact factor: 3.876

8. The C- and N-Terminal Residues of Synthetic Heptapeptide Ion Channels Influence Transport Efficacy Through Phospholipid Bilayers.

Authors: Natasha Djedovič; Riccardo Ferdani; Egan Harder; Jolanta Pajewska; Robert Pajewski; Michelle E Weber; Paul H Schlesinger; George W Gokel
Journal: New J Chem Date: 2005-01-01 Impact factor: 3.591

9. Foxj1 is required for apical localization of ezrin in airway epithelial cells.

Authors: Tao Huang; You You; Melanie S Spoor; Edward J Richer; Vrinda V Kudva; Renee C Paige; Michael P Seiler; Janice M Liebler; Joseph Zabner; Charles G Plopper; Steven L Brody
Journal: J Cell Sci Date: 2003-12-15 Impact factor: 5.285

10. Anion Transport in Liposomes Responds to Variations in the Anchor Chains and the Fourth Amino Acid of Heptapeptide Ion Channels.

Authors: Riccardo Ferdani; Robert Pajewski; Natasha Djedovič; Jolanta Pajewska; Paul H Schlesinger; George W Gokel
Journal: New J Chem Date: 2005 Impact factor: 3.591

10 in total

1. Recent Advances in Synthetic Membrane Transporters.

Authors: Beth A McNally; W Matthew Leevy; Bradley D Smith
Journal: Supramol Chem Date: 2007-01 Impact factor: 1.688

2. Structural and biophysical properties of a synthetic channel-forming peptide: designing a clinically relevant anion selective pore.

Authors: U Bukovnik; J Gao; G A Cook; L P Shank; M B Seabra; B D Schultz; T Iwamoto; J Chen; J M Tomich
Journal: Biochim Biophys Acta Date: 2011-07-31

3. Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia.

Authors: Hongyu Li; Hennie Valkenier; Luke W Judd; Peter R Brotherhood; Sabir Hussain; James A Cooper; Ondřej Jurček; Hazel A Sparkes; David N Sheppard; Anthony P Davis
Journal: Nat Chem Date: 2015-11-02 Impact factor: 24.427

4. Effect of diaminopropionic acid (Dap) on the biophysical properties of a modified synthetic channel-forming peptide.

Authors: Urska Bukovnik; Monica Sala-Rabanal; Simonne Francis; Shawnalea J Frazier; Bruce D Schultz; Colin G Nichols; John M Tomich
Journal: Mol Pharm Date: 2013-09-23 Impact factor: 4.939

5. In vivo cell death mediated by synthetic ion channels.

Authors: Bryan A Smith; Megan M Daschbach; Seth T Gammon; Shuzhang Xiao; Sarah E Chapman; Caroline Hudson; Mark Suckow; David Piwnica-Worms; George W Gokel; W Matthew Leevy
Journal: Chem Commun (Camb) Date: 2011-06-17 Impact factor: 6.222

6. Carboxylate anion diminishes chloride transport through a synthetic, self-assembled transmembrane pore.

Authors: Lei You; Riccardo Ferdani; Ruiqiong Li; Joseph P Kramer; Rudolph Ernst K Winter; George W Gokel
Journal: Chemistry Date: 2008 Impact factor: 5.236

7. Anion transport properties of amine and amide-sidechained peptides are affected by charge and phospholipid composition.

Authors: Lei You; Ruiqiong Li; George W Gokel
Journal: Org Biomol Chem Date: 2008-06-16 Impact factor: 3.876