Literature DB >> 12613586

Anchor chain length alters the apparent mechanism of chloride channel function in SCMTR derivatives.

Paul H Schlesinger1, Natasha K Djedovic, Riccardo Ferdani, Jolanta Pajewska, Robert Pajewski, George W Gokel.   

Abstract

Two membrane-anchored heptapeptides have been prepared and their pore-formation behavior in phospholipid bilayer membranes has been found to differ profoundly as a result only of alkyl chain length.

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Year:  2003        PMID: 12613586     DOI: 10.1039/b211629b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  12 in total

1.  A synthetic, chloride-selective channel that alters chloride transport in epithelial cells.

Authors:  Robert Pajewski; Raquel Garcia-Medina; Steven L Brody; W Matthew Leevy; Paul H Schlesinger; George W Gokel
Journal:  Chem Commun (Camb)       Date:  2005-11-22       Impact factor: 6.222

Review 2.  Development of synthetic membrane transporters for anions.

Authors:  Anthony P Davis; David N Sheppard; Bradley D Smith
Journal:  Chem Soc Rev       Date:  2006-10-23       Impact factor: 54.564

3.  Planar bilayer studies reveal multiple conductance states for synthetic anion transporters.

Authors:  Riccardo Ferdani; George W Gokel
Journal:  Org Biomol Chem       Date:  2006-08-29       Impact factor: 3.876

4.  Evidence for dimer formation by an amphiphilic heptapeptide that mediates chloride and carboxyfluorescein release from liposomes.

Authors:  Robert Pajewski; Riccardo Ferdani; Jolanta Pajewska; Natasha Djedovic; Paul H Schlesinger; George W Gokel
Journal:  Org Biomol Chem       Date:  2005-01-13       Impact factor: 3.876

5.  Carboxylate anion diminishes chloride transport through a synthetic, self-assembled transmembrane pore.

Authors:  Lei You; Riccardo Ferdani; Ruiqiong Li; Joseph P Kramer; Rudolph Ernst K Winter; George W Gokel
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

6.  The C- and N-Terminal Residues of Synthetic Heptapeptide Ion Channels Influence Transport Efficacy Through Phospholipid Bilayers.

Authors:  Natasha Djedovič; Riccardo Ferdani; Egan Harder; Jolanta Pajewska; Robert Pajewski; Michelle E Weber; Paul H Schlesinger; George W Gokel
Journal:  New J Chem       Date:  2005-01-01       Impact factor: 3.591

7.  Aggregation behavior and dynamics of synthetic amphiphiles that self-assemble to anion transporters.

Authors:  Elizabeth K Elliott; Megan M Daschbach; George W Gokel
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

Review 8.  Synthetic, biologically active amphiphilic peptides.

Authors:  Carl R Yamnitz; George W Gokel
Journal:  Chem Biodivers       Date:  2007-06       Impact factor: 2.408

9.  Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides.

Authors:  Neelesh R Soman; Gregory M Lanza; John M Heuser; Paul H Schlesinger; Samuel A Wickline
Journal:  Nano Lett       Date:  2008-02-27       Impact factor: 11.189

10.  Transport of chloride and carboxyfluorescein through phospholipid vesicle membranes by heptapeptide amphiphiles.

Authors:  Riccardo Ferdani; Ruiqiong Li; Robert Pajewski; Jolanta Pajewska; Rudolph K Winter; George W Gokel
Journal:  Org Biomol Chem       Date:  2007-06-25       Impact factor: 3.876

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