Literature DB >> 16389466

The influence of grain size on the ductility of micro-scale stainless steel stent struts.

B P Murphy1, H Cuddy, F J Harewood, T Connolley, P E McHugh.   

Abstract

Vascular stents are used to restore blood flow in stenotic arteries, and at present the implantation of a stent is the preferred revascularisation method for treating coronary artery disease, as the introduction of drug eluting stents (DESs) has lead to a significant improvement in the clinical outcome of coronary stenting. However the mechanical limits of stents are being tested when they are deployed in severe cases. In this study we aimed to show (by a combination of experimental tests and crystal plasticity finite element models) that the ductility of stainless steel stent struts can be increased by optimising the grain structure within micro-scale stainless steel stent struts. The results of the study show that within the specimen size range 55 to 190 microm ductility was not dependent on the size of the stent strut when the grain size maximised. For values of the ratio of cross sectional area to characteristic grain length less than 1,000, ductility was at a minimum irrespective of specimen size. However, when the ratio of cross sectional area to characteristic grain length becomes greater than 1,000 an improvement in ductility occurs, reaching a plateau when the ratio approaches a value characteristic of bulk material properties. In conclusion the ductility of micro-scale stainless steel stent struts is sensitive to microstructure and can be improved by reducing the grain size.

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Year:  2006        PMID: 16389466     DOI: 10.1007/s10856-006-6323-5

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  12 in total

1.  Influence of topography on endothelialization of stents: clues for new designs.

Authors:  C Simon; J C Palmaz; E A Sprague
Journal:  J Long Term Eff Med Implants       Date:  2000

2.  Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trial.

Authors:  Jürgen Pache; Adnan Kastrati; Julinda Mehilli; Helmut Schühlen; Franz Dotzer; Jörg Hausleiter; Martin Fleckenstein; Franz Josef Neumann; Ulrich Sattelberger; Claus Schmitt; Martina Müller; Josef Dirschinger; Albert Schömig
Journal:  J Am Coll Cardiol       Date:  2003-04-16       Impact factor: 24.094

3.  Coronary stent strut size dependent stress-strain response investigated using micromechanical finite element models.

Authors:  P Savage; B P O'Donnell; P E McHugh; B P Murphy; D F Quinn
Journal:  Ann Biomed Eng       Date:  2004-02       Impact factor: 3.934

4.  Impact of strut thickness on late luminal loss after coronary artery stent placement.

Authors:  Saskia Z H Rittersma; Robbert J de Winter; Karel T Koch; Matthijs Bax; Carl E Schotborgh; Karla J Mulder; Jan G P Tijssen; Jan J Piek
Journal:  Am J Cardiol       Date:  2004-02-15       Impact factor: 2.778

Review 5.  Polymer-based paclitaxel-eluting stents in percutaneous coronary intervention: a review of the TAXUS trials.

Authors:  Amir Halkin; Gregg W Stone
Journal:  J Interv Cardiol       Date:  2004-10       Impact factor: 2.279

Review 6.  The approach to small vessels in the era of drug-eluting stents.

Authors:  David R Holmes; Dean J Kereiakes
Journal:  Rev Cardiovasc Med       Date:  2005       Impact factor: 2.930

7.  The importance of annealing 316 LVM stents.

Authors:  C Meyer-Kobbe; B H Hinrichs
Journal:  Med Device Technol       Date:  2003

8.  Coronary-artery stents--gauging, gorging, and gouging.

Authors:  E J Topol
Journal:  N Engl J Med       Date:  1998-12-03       Impact factor: 91.245

9.  Residual stresses in coronary artery stents.

Authors:  D Möller; W Reimers; A Pyzalla; A Fischer
Journal:  J Biomed Mater Res       Date:  2001

10.  Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO) trial.

Authors:  A Kastrati; J Mehilli; J Dirschinger; F Dotzer; H Schühlen; F J Neumann; M Fleckenstein; C Pfafferott; M Seyfarth; A Schömig
Journal:  Circulation       Date:  2001-06-12       Impact factor: 29.690

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  1 in total

1.  Effect of grain sizes on mechanical properties and biodegradation behavior of pure iron for cardiovascular stent application.

Authors:  Camillus Sunday Obayi; Ranna Tolouei; Afghany Mostavan; Carlo Paternoster; Stephane Turgeon; Boniface Adeleh Okorie; Daniel Oray Obikwelu; Diego Mantovani
Journal:  Biomatter       Date:  2016
  1 in total

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