Literature DB >> 16381706

Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: a Monte Carlo study.

M Bues1, W D Newhauser, U Titt, A R Smith.   

Abstract

In step and shoot spot-scanning, a small-diameter proton beam is magnetically swept and varied in energy in order to cover the tumour. Initial estimates of the beam size indicate that additional collimating hardware will be needed for lower energy proton beams in order to achieve a clinically acceptable lateral dose falloff at the edge of the proton beam. In this report, we present dosimetric data from Monte Carlo simulations with a model of a simple multileaf collimator which indicate that such a device may be used to improve the lateral dose falloff. The dosimetric quantities relevant to the clinical usefulness of the device are studied, including lateral penumbra, leaf transmission and scalloping effect. Multileaf collimation is compared with a differential spot-weighting technique of sharpening the lateral dose falloff.

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Year:  2005        PMID: 16381706     DOI: 10.1093/rpd/nci259

Source DB:  PubMed          Journal:  Radiat Prot Dosimetry        ISSN: 0144-8420            Impact factor:   0.972


  26 in total

1.  Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency.

Authors:  Uwe Titt; Dragan Mirkovic; Gabriel O Sawakuchi; Luis A Perles; Wayne D Newhauser; Phillip J Taddei; Radhe Mohan
Journal:  Phys Med Biol       Date:  2010-11-12       Impact factor: 3.609

2.  Monte Carlo and analytical model predictions of leakage neutron exposures from passively scattered proton therapy.

Authors:  Angélica Pérez-Andújar; Rui Zhang; Wayne Newhauser
Journal:  Med Phys       Date:  2013-12       Impact factor: 4.071

3.  Risk of radiogenic second cancers following volumetric modulated arc therapy and proton arc therapy for prostate cancer.

Authors:  Laura A Rechner; Rebecca M Howell; Rui Zhang; Carol Etzel; Andrew K Lee; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2012-10-10       Impact factor: 3.609

4.  Trimmer sequencing time minimization during dynamically collimated proton therapy using a colony of cooperating agents.

Authors:  Blake R Smith; Daniel E Hyer; Ryan T Flynn; Patrick M Hill; Wesley S Culberson
Journal:  Phys Med Biol       Date:  2019-10-21       Impact factor: 3.609

Review 5.  Proton therapy delivery: what is needed in the next ten years?

Authors:  Andries N Schreuder; Jacob Shamblin
Journal:  Br J Radiol       Date:  2019-11-14       Impact factor: 3.039

6.  Comparison of MCNPX and Geant4 proton energy deposition predictions for clinical use.

Authors:  U Titt; B Bednarz; H Paganetti
Journal:  Phys Med Biol       Date:  2012-09-21       Impact factor: 3.609

7.  Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator.

Authors:  David J Brenner; Carl D Elliston; Eric J Hall; Harald Paganetti
Journal:  Phys Med Biol       Date:  2009-09-24       Impact factor: 3.609

8.  Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions.

Authors:  U Titt; N Sahoo; X Ding; Y Zheng; W D Newhauser; X R Zhu; J C Polf; M T Gillin; R Mohan
Journal:  Phys Med Biol       Date:  2008-07-31       Impact factor: 3.609

9.  Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer.

Authors:  Phillip J Taddei; Jonas D Fontenot; Yuanshui Zheng; Dragan Mirkovic; Andrew K Lee; Uwe Titt; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2008-03-27       Impact factor: 3.609

10.  Design of a focused collimator for proton therapy spot scanning using Monte Carlo methods.

Authors:  Theodore J Geoghegan; Nicholas P Nelson; Ryan T Flynn; Patrick M Hill; Suresh Rana; Daniel E Hyer
Journal:  Med Phys       Date:  2020-04-06       Impact factor: 4.071

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