PURPOSE: To measure the apparent diffusion coefficient (ADC) of normal and malignant prostate tissue at 3.0T using a phased-array coil and parallel imaging, and determine the utility of ADC values in differentiating tumor from normal peripheral zone (PZ). MATERIALS AND METHODS: ADC values were calculated for 49 patients (tumor and PZ) with evidence of prostate cancer. Additionally, for nine asymptomatic volunteers, ADC values were determined for apparently normal central gland and PZ. A single-shot EPI diffusion-weighted imaging (DWI) technique with b = 0 and 500 seconds/mm2 was employed. RESULTS: ADC values were significantly lower for tumor (1.38 +/- 0.32 x 10(-3) mm2/second) than for patient PZ (1.95 +/- 0.50 x 10(-3) mm2/second, P < 0.001) and volunteer PZ (1.60 +/- 0.25 x 10(-3) mm2/second, P = 0.031). A considerable overlap of ADC values was noted between patient tissue types. CONCLUSION: DWI of the prostate at 3.0T in conjunction with a phased-array coil and parallel imaging allows ADC calculation of the prostate. ADC values were lower for tumors compared to normal-appearing PZ; however, there was considerable intersubject variability. (c) 2005 Wiley-Liss, Inc.
PURPOSE: To measure the apparent diffusion coefficient (ADC) of normal and malignant prostate tissue at 3.0T using a phased-array coil and parallel imaging, and determine the utility of ADC values in differentiating tumor from normal peripheral zone (PZ). MATERIALS AND METHODS: ADC values were calculated for 49 patients (tumor and PZ) with evidence of prostate cancer. Additionally, for nine asymptomatic volunteers, ADC values were determined for apparently normal central gland and PZ. A single-shot EPI diffusion-weighted imaging (DWI) technique with b = 0 and 500 seconds/mm2 was employed. RESULTS: ADC values were significantly lower for tumor (1.38 +/- 0.32 x 10(-3) mm2/second) than for patient PZ (1.95 +/- 0.50 x 10(-3) mm2/second, P < 0.001) and volunteer PZ (1.60 +/- 0.25 x 10(-3) mm2/second, P = 0.031). A considerable overlap of ADC values was noted between patient tissue types. CONCLUSION: DWI of the prostate at 3.0T in conjunction with a phased-array coil and parallel imaging allows ADC calculation of the prostate. ADC values were lower for tumors compared to normal-appearing PZ; however, there was considerable intersubject variability. (c) 2005 Wiley-Liss, Inc.
Authors: Carlos F Uribe; Edward C Jones; Silvia D Chang; S Larry Goldenberg; Stefan A Reinsberg; Piotr Kozlowski Journal: Magn Reson Imaging Date: 2015-02-24 Impact factor: 2.546
Authors: Antonio C Westphalen; Galen D Reed; Phillip P Vinh; Christopher Sotto; Daniel B Vigneron; John Kurhanewicz Journal: J Magn Reson Imaging Date: 2012-04-25 Impact factor: 4.813
Authors: Alice C Yu; Chaitra Badve; Lee E Ponsky; Shivani Pahwa; Sara Dastmalchian; Matthew Rogers; Yun Jiang; Seunghee Margevicius; Mark Schluchter; William Tabayoyong; Robert Abouassaly; Debra McGivney; Mark A Griswold; Vikas Gulani Journal: Radiology Date: 2017-02-10 Impact factor: 11.105
Authors: Junqian Xu; Peter A Humphrey; Adam S Kibel; Abraham Z Snyder; Vamsidhar R Narra; Joseph J H Ackerman; Sheng-Kwei Song Journal: Magn Reson Med Date: 2009-04 Impact factor: 4.668