Literature DB >> 16345499

Production and biological activity of secalonic Acid d.

A Ciegler1, A W Hayes, R F Vesonder.   

Abstract

Twenty isolates of Penicillium oxalicum produced secalonic acid as their major secondary metabolite. Fermentation conditions were determined for toxin production in grain and liquid media. The 50% lethal dose value for mice ranged from 26.5 to 51.7 mg/kg dependent on animal strain and sex, males being more susceptible than females. Secalonic acid was nontoxic and nonteratogenic to the chicken embryo and exhibited poor antibiotic properties. Its potential role in mycotoxicoses is discussed.

Entities:  

Year:  1980        PMID： 16345499      PMCID： PMC291324          DOI： 10.1128/aem.39.2.285-287.1980

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  8 in total

1.  Fungal metabolites. 1. Stereochemical features and mass spectrometry secalonic acids.

Authors:  C C Howard; R A Johnstone
Journal:  J Chem Soc Perkin 1       Date:  1973

2.  The isolation, structure and absolute configuration of secalonic acid D, the toxic metabolite of Penicillium oxalicum.

Authors:  P S Steyn
Journal:  Tetrahedron       Date:  1970-01       Impact factor: 2.457

3.  The isolation of secalonic acid A from Aspergillus ochraceus cultured on rice.

Authors:  M Yamazaki; Y Maebayashi; K Miyaki
Journal:  Chem Pharm Bull (Tokyo)       Date:  1971-01       Impact factor: 1.645

4.  Investigations of the toxic effects in mice of certain species of Penicillium.

Authors:  W W Carlton; J Tuite; P Mislivec
Journal:  Toxicol Appl Pharmacol       Date:  1968-11       Impact factor: 4.219

5.  Produciton and biological activity of patulin and citrinin from Penicillium expansum.

Authors:  A Ciegler; R F Vesonder; L K Jackson
Journal:  Appl Environ Microbiol       Date:  1977-04       Impact factor: 4.792

6.  Secalonic acids D and F are toxic metabolites of Aspergillus aculeatus.

Authors:  R Andersen; G Büchi; B Kobbe; A L Demain
Journal:  J Org Chem       Date:  1977-01-21       Impact factor: 4.354

7.  Causative fungus agent of leucoencephalomalacia in equine animals.

Authors:  B J Wilson; R R Maronpot
Journal:  Vet Rec       Date:  1971-05-08       Impact factor: 2.695

8.  Toxigenic fungi isolated from cereal and legume products.

Authors:  D B Scott
Journal:  Mycopathol Mycol Appl       Date:  1965-04-14
  8 in total
  6 in total

1.  Secalonic acid D: natural contaminant of corn dust.

Authors:  K C Ehrlich; L S Lee; A Ciegler; M S Palmgren
Journal:  Appl Environ Microbiol       Date:  1982-10       Impact factor: 4.792

2.  Enzyme-linked immunosorbent assay for secalonic acid D.

Authors:  J N Neucere
Journal:  Mycopathologia       Date:  1986-01       Impact factor: 2.574

3.  Enhancement of influenza virus infections by secalonic acid D.

Authors:  D S Fleischhacker; T G Akers; S P Katz; M S Palmgren
Journal:  Environ Health Perspect       Date:  1986-04       Impact factor: 9.031

4.  Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi.

Authors:  Claudio Greco; Kate de Mattos-Shipley; Andrew M Bailey; Nicholas P Mulholland; Jason L Vincent; Christine L Willis; Russell J Cox; Thomas J Simpson
Journal:  Chem Sci       Date:  2019-01-21       Impact factor: 9.825

5.  Ergochromes: Heretofore Neglected Side of Ergot Toxicity.

Authors:  Miroslav Flieger; Eva Stodůlková; Stephen A Wyka; Jan Černý; Valéria Grobárová; Kamila Píchová; Petr Novák; Petr Man; Marek Kuzma; Ladislav Cvak; Kirk D Broders; Miroslav Kolařík
Journal:  Toxins (Basel)       Date:  2019-07-25       Impact factor: 4.546

6.  Separation of mycotoxin-containing sources in grain dust and determination of their mycotoxin potential.

Authors:  M S Palmgren; L S Lee
Journal:  Environ Health Perspect       Date:  1986-04       Impact factor: 9.031
  6 in total

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