| Literature DB >> 16339440 |
R P Goodman1, I A T Schaap, C F Tardin, C M Erben, R M Berry, C F Schmidt, A J Turberfield.
Abstract
Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on a side, that can self-assemble in seconds with near-quantitative yield of one diastereomer. They can be connected by programmable DNA linkers. Their triangulated architecture confers structural stability; by compressing a DNA tetrahedron with an atomic force microscope, we have measured the axial compressibility of DNA and observed the buckling of the double helix under high loads.Mesh：
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Year: 2005 PMID： 16339440 DOI： 10.1126/science.1120367
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728