Literature DB >> 16338589

Antibacterial activity directed isolation of compounds from Onosma hispidum.

Shahina Naz1, Samia Ahmad, Sheikh Ajaz Rasool, Syed Asad Sayeed, Rahmanullah Siddiqi.   

Abstract

The chemical investigation of the ethanolic extract of the root bark of Onosma hispidum following antibacterial activity directed isolation led to the isolation of 4-hydroxy-3-methoxy cinnamic acid (ferulic acid) and 4-hydroxy-3-methoxy benzoic acid (vanillic acid) which have been reported for the first time in this species. In addition to these compounds, the crude ethanolic extract and methanol fraction exhibited substantial bioactivity against species of corynebacteria, enterococci, staphylococci and streptococci. Ferulic acid was found more bioactive (being relatively more hydrophobic) compared to vanillic acid.

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Year:  2005        PMID： 16338589     DOI： 10.1016/j.micres.2005.05.001

Source DB:  PubMed          Journal:  Microbiol Res        ISSN： 0944-5013            Impact factor:   5.415


  23 in total

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4.  (2E)-N'-Benzoyl-3-(4-nitro-phen-yl)prop-2-enohydrazide.

Authors:  Samir A Carvalho; Edson F da Silva; Marcus V N de Souza; Edward R T Tiekink; James L Wardell; Solange M S V Wardell
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5.  (2E)-N'-[(E)-4-Chloro-benzyl-idene]-3-phenyl-prop-2-enohydrazide monohydrate.

Authors:  Samir A Carvalho; Edson F da Silva; Carlos A M Fraga; Solange M S V Wardell; James L Wardell; Edward R T Tiekink
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7.  Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone.

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8.  Chemical Composition, Antioxidant and Enzyme Inhibitory Activities of Onosma bourgaei and Onosma trachytricha and in Silico Molecular Docking Analysis of Dominant Compounds.

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Journal:  Molecules       Date:  2021-05-18       Impact factor: 4.411

9.  Binding effect of proline-rich-proteins (PRPs) on in vitro antimicrobial activity of the flavonoids.

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Journal:  Braz J Microbiol       Date:  2015-03-01       Impact factor: 2.476

Review 10.  Onosma L.: A review of phytochemistry and ethnopharmacology.

Authors:  Neeraj Kumar; Rajnish Kumar; Kamal Kishore
Journal:  Pharmacogn Rev       Date:  2013-07
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