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Literature DB >> 16307142

Multivalent, bifunctional dendrimers prepared by click chemistry.

Peng Wu¹, Michael Malkoch, Jasmine N Hunt, Robert Vestberg, Eiton Kaltgrad, M G Finn, Valery V Fokin, K Barry Sharpless, Craig J Hawker.

Abstract

Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.

Entities: Chemical

Mesh：

Substances：
Dendrimers
Acetylene

Year: 2005 PMID： 16307142 DOI： 10.1039/b512021g

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

Keyword Cloud
Cited

39 in total

Review 1. Polymeric carriers for gene delivery: chitosan and poly(amidoamine) dendrimers.

Authors: Qingxing Xu; Chi-Hwa Wang; Daniel Wayne Pack
Journal: Curr Pharm Des Date: 2010-07 Impact factor: 3.116

Review 2. Click chemistry with polymers, dendrimers, and hydrogels for drug delivery.

Authors: Enrique Lallana; Francisco Fernandez-Trillo; Ana Sousa-Herves; Ricardo Riguera; Eduardo Fernandez-Megia
Journal: Pharm Res Date: 2012-01-25 Impact factor: 4.200

3. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

Authors: Douglas G Mullen; Daniel Q McNerny; Ankur Desai; Xue-Min Cheng; Stassi C Dimaggio; Alina Kotlyar; Yueyang Zhong; Suyang Qin; Christopher V Kelly; Thommey P Thomas; Istvan Majoros; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal: Bioconjug Chem Date: 2011-03-22 Impact factor: 4.774

4. Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions.

Authors: Kunsang Yoon; Poorva Goyal; Marcus Weck
Journal: Org Lett Date: 2007-05-02 Impact factor: 6.005

5. Effect of mannose targeting of hydroxyl PAMAM dendrimers on cellular and organ biodistribution in a neonatal brain injury model.

Authors: Anjali Sharma; Joshua E Porterfield; Elizabeth Smith; Rishi Sharma; Sujatha Kannan; Rangaramanujam M Kannan
Journal: J Control Release Date: 2018-06-05 Impact factor: 9.776

Multivalent, bifunctional dendrimers prepared by click chemistry.

Review 1. Polymeric carriers for gene delivery: chitosan and poly(amidoamine) dendrimers.

Review 2. Click chemistry with polymers, dendrimers, and hydrogels for drug delivery.

3. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

4. Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions.

5. Effect of mannose targeting of hydroxyl PAMAM dendrimers on cellular and organ biodistribution in a neonatal brain injury model.

6. Tuning thermoresponsive supramolecular G-quadruplexes.

Review 7. Applications of orthogonal "click" chemistries in the synthesis of functional soft materials.

8. Nanotechnology of emerging targeting systems.

9. Highly efficient "grafting onto" a polypeptide backbone using click chemistry.

10. Efficient synthesis of fluorescent squaraine rotaxane dendrimers.