Literature DB >> 17472392

Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions.

Kunsang Yoon1, Poorva Goyal, Marcus Weck.   

Abstract

Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.

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Year:  2007        PMID： 17472392      PMCID： PMC2559814          DOI： 10.1021/ol062949h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  24 in total

1.  Click Chemistry: Diverse Chemical Function from a Few Good Reactions.

Authors:  Hartmuth C. Kolb; M. G. Finn; K. Barry Sharpless
Journal:  Angew Chem Int Ed Engl       Date:  2001-06-01       Impact factor: 15.336

2.  About Dendrimers: Structure, Physical Properties, and Applications.

Authors:  A. W. Bosman; H. M. Janssen; E. W. Meijer
Journal:  Chem Rev       Date:  1999-07-14       Impact factor: 60.622

Review 3.  Biological applications of dendrimers.

Authors:  Mary J Cloninger
Journal:  Curr Opin Chem Biol       Date:  2002-12       Impact factor: 8.822

4.  Individual water-soluble dendrimer-encapsulated silver nanodot fluorescence.

Authors:  Jie Zheng; Robert M Dickson
Journal:  J Am Chem Soc       Date:  2002-11-27       Impact factor: 15.419

5.  Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry.

Authors:  Dirk T S Rijkers; G Wilma van Esse; Remco Merkx; Arwin J Brouwer; Hans J F Jacobs; Roland J Pieters; Rob M J Liskamp
Journal:  Chem Commun (Camb)       Date:  2005-08-19       Impact factor: 6.222

6.  Functionalization of polymers with phosphorescent iridium complexes via click chemistry.

Authors:  Xian-Yong Wang; Alpay Kimyonok; Marcus Weck
Journal:  Chem Commun (Camb)       Date:  2006-08-09       Impact factor: 6.222

7.  Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications.

Authors:  R Esfand; D A. Tomalia
Journal:  Drug Discov Today       Date:  2001-04-01       Impact factor: 7.851

8.  Microwave assisted "click" chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support.

Authors:  Camille Bouillon; Albert Meyer; Sébastien Vidal; Anne Jochum; Yann Chevolot; Jean-Pierre Cloarec; Jean-Pierre Praly; Jean-Jacques Vasseur; François Morvan
Journal:  J Org Chem       Date:  2006-06-09       Impact factor: 4.354

Review 9.  The convergence of synthetic organic and polymer chemistries.

Authors:  Craig J Hawker; Karen L Wooley
Journal:  Science       Date:  2005-08-19       Impact factor: 47.728

10.  A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-sulfonyl tetrazoles from azides and sulfonyl cyanides.

Authors:  Zachary P Demko; K Barry Sharpless
Journal:  Angew Chem Int Ed Engl       Date:  2002-06-17       Impact factor: 15.336
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  6 in total

1.  Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

Authors:  Douglas G Mullen; Daniel Q McNerny; Ankur Desai; Xue-Min Cheng; Stassi C Dimaggio; Alina Kotlyar; Yueyang Zhong; Suyang Qin; Christopher V Kelly; Thommey P Thomas; Istvan Majoros; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal:  Bioconjug Chem       Date:  2011-03-22       Impact factor: 4.774

2.  Heterogeneous ligand-nanoparticle distributions: a major obstacle to scientific understanding and commercial translation.

Authors:  Douglas G Mullen; Mark M Banaszak Holl
Journal:  Acc Chem Res       Date:  2011-08-03       Impact factor: 22.384

3.  Self-interrupted synthesis of sterically hindered aliphatic polyamide dendrimers.

Authors:  Davit Jishkariani; Christopher M MacDermaid; Yam N Timsina; Silvia Grama; Syeda S Gillani; Masoumeh Divar; Srujana S Yadavalli; Ralph-Olivier Moussodia; Pawaret Leowanawat; Angely M Berrios Camacho; Ricardo Walter; Mark Goulian; Michael L Klein; Virgil Percec
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-07       Impact factor: 11.205

4.  Exhaustive glycosylation, PEGylation, and glutathionylation of a [G4]-ene(48) dendrimer via photoinduced thiol-ene coupling.

Authors:  Mauro Lo Conte; Maxwell J Robb; Yvonne Hed; Alberto Marra; Michael Malkoch; Craig J Hawker; Alessandro Dondoni
Journal:  J Polym Sci A Polym Chem       Date:  2011-10-15       Impact factor: 2.702

5.  Efficient modification of PAMAM G1 dendrimer surface with β-cyclodextrin units by CuAAC: impact on the water solubility and cytotoxicity.

Authors:  Kendra Sorroza-Martínez; Israel González-Méndez; Ricardo D Martínez-Serrano; José D Solano; Andrea Ruiu; Javier Illescas; Xiao Xia Zhu; Ernesto Rivera
Journal:  RSC Adv       Date:  2020-07-07       Impact factor: 4.036

6.  Hyperbranched polydendrons: a new nanomaterials platform with tuneable permeation through model gut epithelium.

Authors:  Fiona L Hatton; Lee M Tatham; Louise R Tidbury; Pierre Chambon; Tao He; Andrew Owen; Steven P Rannard
Journal:  Chem Sci       Date:  2014-10-03       Impact factor: 9.825
  6 in total

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