| Literature DB >> 16304600 |
François Pompanon1, Aurélie Bonin, Eva Bellemain, Pierre Taberlet.
Abstract
Although genotyping errors affect most data and can markedly influence the biological conclusions of a study, they are too often neglected. Errors have various causes, but their occurrence and effect can be limited by considering these causes in the production and analysis of the data. Procedures that have been developed for dealing with errors in linkage studies, forensic analyses and non-invasive genotyping should be applied more broadly to any genetic study. We propose a protocol for estimating error rates and recommend that these measures be systemically reported to attest the reliability of published genotyping studies.Mesh：
Year: 2005 PMID： 16304600 DOI： 10.1038/nrg1707
Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242