| Literature DB >> 16304183 |
Joel Tarning1, Niklas Lindegårdh, Anna Annerberg, Thida Singtoroj, Nicholas P J Day, Michael Ashton, Nicholas J White.
Abstract
By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs.Entities:
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Year: 2005 PMID: 16304183 PMCID: PMC1315981 DOI: 10.1128/AAC.49.12.5127-5128.2005
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191