| Literature DB >> 16297615 |
Xiu-feng Zhang1, Hong-mei Wang, Yuan-li Song, Li-hua Nie, Lan-fen Wang, Bin Liu, Ping-ping Shen, Yang Liu.
Abstract
Two new dihydrocoumarin derivatives, compounds 1 and 2, were isolated from Aloe vera. Their structures were determined by X-ray crystallographic diffraction analysis and extensive 1D, 2D NMR spectroscopic data. Both of them evidently showed antioxidant activity against superoxide and hydroxyl radicals. Only 1 obviously exhibited immunomodulatory activity in relation to increasing the phagocytic activity and stimulating the production of superoxide anions in the oxygen respiratory burst of rat peritoneal macrophages.Entities:
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Year: 2005 PMID： 16297615 DOI： 10.1016/j.bmcl.2005.10.096
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823