Literature DB >> 16296768

Liposomes in the treatment of inflammatory disorders.

Josbert M Metselaar1, Gert Storm.   

Abstract

This review focuses on the therapeutic utility of liposomes in the treatment of inflammatory disorders, and aims to offer the reader an overview of the in vivo results obtained with liposomally encapsulated anti-inflammatory and immune suppressive drugs. The past 30 years has clearly indicated the added value of liposomes in the search for solutions for the delivery problems encountered. However, only a few liposomal anti-inflammatory therapeutics have entered the clinic. Reasons for the hurdles existing in the translation of promising preclinical findings to clinical studies are discussed.

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Year:  2005        PMID： 16296768     DOI： 10.1517/17425247.2.3.465

Source DB:  PubMed          Journal:  Expert Opin Drug Deliv        ISSN： 1742-5247            Impact factor:   6.648


  23 in total

Review 1.  Strategies to target drugs to gliomas and CNS metastases of solid tumors.

Authors:  B Milojkovic Kerklaan; O van Tellingen; A D R Huitema; J H Beijnen; W Boogerd; J H M Schellens; D Brandsma
Journal:  J Neurol       Date:  2015-10-17       Impact factor: 4.849

Review 2.  Therapeutic targeting of trained immunity.

Authors:  Willem J M Mulder; Jordi Ochando; Leo A B Joosten; Zahi A Fayad; Mihai G Netea
Journal:  Nat Rev Drug Discov       Date:  2019-07       Impact factor: 84.694

3.  Imaging the efficacy of anti-inflammatory liposomes in a rabbit model of atherosclerosis by non-invasive imaging.

Authors:  Mark E Lobatto; Claudia Calcagno; Josbert M Metselaar; Gert Storm; Erik S G Stroes; Zahi A Fayad; Willem J M Mulder
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

4.  Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall.

Authors:  Mark E Lobatto; Tina Binderup; Philip M Robson; Luuk F P Giesen; Claudia Calcagno; Julia Witjes; Francois Fay; Samantha Baxter; Chang Ho Wessel; Mootaz Eldib; Jason Bini; Sean D Carlin; Erik S G Stroes; Gert Storm; Andreas Kjaer; Jason S Lewis; Thomas Reiner; Zahi A Fayad; Willem J M Mulder; Carlos Pérez-Medina
Journal:  Bioconjug Chem       Date:  2019-06-07       Impact factor: 4.774

5.  Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis.

Authors:  Mark E Lobatto; Zahi A Fayad; Stephane Silvera; Esad Vucic; Claudia Calcagno; Venkatesh Mani; Stephen D Dickson; Klaas Nicolay; Manuela Banciu; Raymond M Schiffelers; Josbert M Metselaar; Louis van Bloois; Hai-Shan Wu; John T Fallon; James H Rudd; Valentin Fuster; Edward A Fisher; Gert Storm; Willem J M Mulder
Journal:  Mol Pharm       Date:  2010-11-08       Impact factor: 4.939

6.  Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.

Authors:  Yuval Avnir; Keren Turjeman; Deborah Tulchinsky; Alex Sigal; Pablo Kizelsztein; Dina Tzemach; Alberto Gabizon; Yechezkel Barenholz
Journal:  PLoS One       Date:  2011-10-06       Impact factor: 3.240

7.  Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.

Authors:  Huan Wang; Yifan Ding; Wei Zhang; Kang Wei; Yaping Pei; Chenming Zou; Chong Zhang; Jiahui Ding; Huang Fang; Songwei Tan
Journal:  Drug Des Devel Ther       Date:  2020-02-28       Impact factor: 4.162

Review 8.  Peptide-functionalized liposomes as therapeutic and diagnostic tools for cancer treatment.

Authors:  Jafrin Jobayer Sonju; Achyut Dahal; Sitanshu S Singh; Seetharama D Jois
Journal:  J Control Release       Date:  2020-10-01       Impact factor: 9.776

9.  Enhanced antitumor immune response in melanoma tumor model by anti-PD-1 small interference RNA encapsulated in nanoliposomes.

Authors:  Mehdi Barati; Farshad Mirzavi; Amin Reza Nikpoor; Mojtaba Sankian; Hasan Namdar Ahmadabad; Anvar Soleimani; Mohammad Mashreghi; Jalil Tavakol Afshar; Mojgan Mohammadi; Mahmoud Reza Jaafari
Journal:  Cancer Gene Ther       Date:  2021-08-02       Impact factor: 5.854

Review 10.  Drug delivery and nanoparticles:applications and hazards.

Authors:  Wim H De Jong; Paul J A Borm
Journal:  Int J Nanomedicine       Date:  2008
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