Literature DB >> 16269325

The proteasome: not just degrading anymore.

Stephen P Baker1, Patrick A Grant.   

Abstract

The proteasome is a large multiprotein complex that has a critical role in the degradation of ubiquitylated proteins. A fascinating paper in this issue of Cell (Lee et al., 2005) now reveals that the proteasome recruits the SAGA histone acetyltransferase complex to a target promoter during gene activation. This finding adds to the growing body of evidence indicating that the proteasome has nonproteolytic functions.

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Substances:

Year:  2005        PMID: 16269325     DOI: 10.1016/j.cell.2005.10.013

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  11 in total

Review 1.  Emerging roles of the 26S proteasome in nuclear hormone receptor-regulated transcription.

Authors:  Brian R Keppler; Trevor K Archer; H Karimi Kinyamu
Journal:  Biochim Biophys Acta       Date:  2010-08-20

Review 2.  The SAGA continues: expanding the cellular role of a transcriptional co-activator complex.

Authors:  S P Baker; P A Grant
Journal:  Oncogene       Date:  2007-08-13       Impact factor: 9.867

3.  Nuclear effects of ethanol-induced proteasome inhibition in liver cells.

Authors:  Fawzia Bardag-Gorce
Journal:  World J Gastroenterol       Date:  2009-03-14       Impact factor: 5.742

4.  The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription.

Authors:  Hua Zhang; Luyang Sun; Jing Liang; Wenhua Yu; Ying Zhang; Yan Wang; Yupeng Chen; Ruifang Li; Xiaojing Sun; Yongfeng Shang
Journal:  EMBO J       Date:  2006-09-07       Impact factor: 11.598

5.  Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription.

Authors:  H Karimi Kinyamu; Trevor K Archer
Journal:  Mol Cell Biol       Date:  2007-04-16       Impact factor: 4.272

Review 6.  Structure characterization of the 26S proteasome.

Authors:  Ho Min Kim; Yadong Yu; Yifan Cheng
Journal:  Biochim Biophys Acta       Date:  2010-08-26

Review 7.  Complex genomic interactions in the dynamic regulation of transcription by the glucocorticoid receptor.

Authors:  Tina B Miranda; Stephanie A Morris; Gordon L Hager
Journal:  Mol Cell Endocrinol       Date:  2013-03-14       Impact factor: 4.102

8.  Genome wide transcriptional profiling in breast cancer cells reveals distinct changes in hormone receptor target genes and chromatin modifying enzymes after proteasome inhibition.

Authors:  H Karimi Kinyamu; Jennifer B Collins; Sherry F Grissom; Pratibha B Hebbar; Trevor K Archer
Journal:  Mol Carcinog       Date:  2008-11       Impact factor: 4.784

9.  Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex.

Authors:  Valerie P Zediak; Shelley L Berger
Journal:  Mol Cell       Date:  2008-09-26       Impact factor: 17.970

10.  Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.

Authors:  Erwann Rousseau; Rieko Kojima; Guylaine Hoffner; Philippe Djian; Anne Bertolotti
Journal:  J Biol Chem       Date:  2008-11-05       Impact factor: 5.157

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