Literature DB >> 16259133

Effect of different phenolic compounds on alpha-amylase activity: screening by microplate-reader based kinetic assay.

I Funke1, M F Melzig.   

Abstract

The inhibitory effect of different polyphenolic plant compounds on alpha-amylase activity was investigated in vitro. A kinetic assay was performed using 96-well-plates. Acarbose was used as positive control (IC50: 23.2 microM). Some of the tested compounds, occurring in plants traditionally used in anti-diabetic tea species, showed an inhibition of the enzyme in physiological concentrations, e.g. luteolin, tannic acid, and isochlorogenic acid.

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Year:  2005        PMID： 16259133

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  12 in total

1.  Capillary electrophoresis as a screening tool for alpha amylase inhibitors in plant extracts.

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Authors:  Rosa Tundis; Monica R Loizzo; Marco Bonesi; Vincenzo Sicari; Claudia Ursino; Ilaria Manfredi; Carmela Conidi; Alberto Figoli; Alfredo Cassano
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Journal:  Microorganisms       Date:  2022-05-07

Review 4.  Impact of dietary polyphenols on carbohydrate metabolism.

Authors:  Kati Hanhineva; Riitta Törrönen; Isabel Bondia-Pons; Jenna Pekkinen; Marjukka Kolehmainen; Hannu Mykkänen; Kaisa Poutanen
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5.  The Antioxidant and Starch Hydrolase Inhibitory Activity of Ten Spices in an In Vitro Model of Digestion: Bioaccessibility of Anthocyanins and Carotenoids.

Authors:  Nilakshi Jayawardena; Mindani I Watawana; Ruchini T Jayathilaka; Viduranga Y Waisundara
Journal:  Evid Based Complement Alternat Med       Date:  2015-11-29       Impact factor: 2.629

6.  In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans.

Authors:  Md Ariful Alam; I S M Zaidul; Kashif Ghafoor; F Sahena; M A Hakim; M Y Rafii; H M Abir; M F Bostanudin; V Perumal; A Khatib
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7.  Tropical plant extracts as potential antihyperglycemic agents.

Authors:  Thamilvaani Manaharan; Uma Devi Palanisamy; Cheng Hwee Ming
Journal:  Molecules       Date:  2012-05-18       Impact factor: 4.411

8.  Chlorogenic and phenolic acids are only very weak inhibitors of human salivary α-amylase and rat intestinal maltase activities.

Authors:  Hilda Nyambe-Silavwe; Gary Williamson
Journal:  Food Res Int       Date:  2018-07-30       Impact factor: 6.475

9.  In Vitro α-Glucosidase and α-Amylase Inhibitory Activities of Free and Bound Phenolic Extracts from the Bran and Kernel Fractions of Five Sorghum Grain Genotypes.

Authors:  Yun Xiong; Ken Ng; Pangzhen Zhang; Robyn Dorothy Warner; Shuibao Shen; Hsi-Yang Tang; Zijian Liang; Zhongxiang Fang
Journal:  Foods       Date:  2020-09-15

Review 10.  [Inhibitors of alpha-amylase from plants--a possibility to treat diabetes mellitus type II by phytotherapy?].

Authors:  Matthias F Melzig; Ines Funke
Journal:  Wien Med Wochenschr       Date:  2007
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