Literature DB >> 16222266

Drug discovery: playing dirty.

Simon Frantz.   

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Year:  2005        PMID: 16222266     DOI: 10.1038/437942a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  85 in total

1.  Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors.

Authors:  William Guerrant; Vishal Patil; Joshua C Canzoneri; Adegboyega K Oyelere
Journal:  J Med Chem       Date:  2012-02-13       Impact factor: 7.446

2.  Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization.

Authors:  Janet N Y Chan; Dajana Vuckovic; Lekha Sleno; Jonathan B Olsen; Oxana Pogoutse; Pierre Havugimana; Johannes A Hewel; Navgeet Bajaj; Yale Wang; Marcel F Musteata; Corey Nislow; Andrew Emili
Journal:  Mol Cell Proteomics       Date:  2012-02-22       Impact factor: 5.911

3.  Integrated mechanistic and data-driven modelling for multivariate analysis of signalling pathways.

Authors:  Fei Hua; Sampsa Hautaniemi; Rayka Yokoo; Douglas A Lauffenburger
Journal:  J R Soc Interface       Date:  2006-08-22       Impact factor: 4.118

Review 4.  Decompartmentalizing target validation-thinking outside the pipeline boxes.

Authors:  Rob Hooft van Huijsduijnen; Christian Rommel
Journal:  J Mol Med (Berl)       Date:  2006-08-05       Impact factor: 4.599

5.  Proteome interrogation using nanoprobes to identify targets of a cancer-killing molecule.

Authors:  Liwen Li; Qiu Zhang; Aifeng Liu; Xiue Li; Hongyu Zhou; Yin Liu; Bing Yan
Journal:  J Am Chem Soc       Date:  2011-04-15       Impact factor: 15.419

Review 6.  Drug repositioning: playing dirty to kill pain.

Authors:  Leandro Francisco Silva Bastos; Márcio Matos Coelho
Journal:  CNS Drugs       Date:  2014-01       Impact factor: 5.749

7.  Identification of diaryl 5-amino-1,2,4-oxadiazoles as tubulin inhibitors: the special case of 3-(2-fluorophenyl)-5-(4-methoxyphenyl)amino-1,2,4-oxadiazole.

Authors:  Andrei A Gakh; Andrey V Sosnov; Mikhail Krasavin; Tam Luong Nguyen; Ernest Hamel
Journal:  Bioorg Med Chem Lett       Date:  2013-01-11       Impact factor: 2.823

Review 8.  Chemokine receptor antagonists: overcoming developmental hurdles.

Authors:  Richard Horuk
Journal:  Nat Rev Drug Discov       Date:  2008-12-12       Impact factor: 84.694

9.  Protective effects of Jiashen Prescription () on myocardial infarction in rats.

Authors:  Ming-Jun Zhu; You-Ping Wang; Shi-Yang Xie; Wei-Hong Liu; Bin Li; Yong-Xia Wang; He Wang; Bo-Li Zhang
Journal:  Chin J Integr Med       Date:  2014-05-10       Impact factor: 1.978

Review 10.  1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets.

Authors:  U Das; R K Sharma; J R Dimmock
Journal:  Curr Med Chem       Date:  2009       Impact factor: 4.530

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