Literature DB >> 16214513

In vitro evaluation of aortic valve prosthesis in a novel valved conduit with pseudosinuses of Valsalva.

Ruggero De Paulis1, Christoph Schmitz, Raffaele Scaffa, Paolo Nardi, Luigi Chiariello, Helmut Reul.   

Abstract

OBJECTIVE: This study was undertaken to determine whether the presence of vortices immediately above a prosthetic aortic valve could negatively influence the in vitro hydrodynamic performances of a biologic or mechanical valve implanted in a new Dacron polyester fabric conduit that incorporates sculpted sinuses of Valsalva.
METHODS: With a computer-controlled pulse duplicator, the in vitro performance (pressure differences, closure and leakage volumes, and energy losses) of a 25-mm mechanical or biologic prosthesis implanted in a standard Dacron straight conduit or in the new Dacron graft with a sculpted sinus were analyzed and compared.
RESULTS: The mechanical and biologic prostheses at 7 L/min cardiac output showed pressure drops across the valve of 8.72 mm Hg and 13.45 mm Hg, respectively, when inserted in the new Valsalva-style graft and of 7.97 mm Hg and 12.94 mm Hg, respectively, when inserted in the standard graft. The closure and leakage volumes for mechanical valves were higher than those for biologic valves; however, the presence or absence of sinuses did not result in significant differences in closure and leakage volumes. The maximal total energy losses were 5.89% and 9.49% for mechanical and biologic valves, respectively. No differences were evident between the two different Dacron grafts for each prosthetic heart valve.
CONCLUSION: The normal opening and closing behavior of a prosthetic aortic valve was not altered or modified by a different root shape above the heart valve. The presence of vortices inside the pseudosinuses of Valsalva did not influence the hydrodynamic properties of the biologic and mechanical valves tested.

Mesh:

Year:  2005        PMID: 16214513     DOI: 10.1016/j.jtcvs.2005.04.028

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  4 in total

1.  Realistic Vascular Replicator for TAVR Procedures.

Authors:  Oren M Rotman; Brandon Kovarovic; Chander Sadasivan; Luis Gruberg; Baruch B Lieber; Danny Bluestein
Journal:  Cardiovasc Eng Technol       Date:  2018-04-13       Impact factor: 2.495

2.  Experimental Validation of a Cardiac Simulator for in vitro Evaluation of Prosthetic Heart Valves.

Authors:  Ovandir Bazan; Jayme Pinto Ortiz
Journal:  Braz J Cardiovasc Surg       Date:  2016-04

3.  Duration of Systole and Diastole for Hydrodynamic Testing of Prosthetic Heart Valves: Comparison Between ISO 5840 Standards and in vivo Studies.

Authors:  Ovandir Bazan; Jayme Pinto Ortiz
Journal:  Braz J Cardiovasc Surg       Date:  2016-04

4.  Laser Doppler anemometry measurements of steady flow through two bi-leaflet prosthetic heart valves.

Authors:  Ovandir Bazan; Jayme Pinto Ortiz; Francisco Ubaldo Vieira; Reinaldo Wilson Vieira; Nilson Antunes; Fabio Bittencourt Dutra Tabacow; Eduardo Tavares Costa; Orlando Petrucci
Journal:  Rev Bras Cir Cardiovasc       Date:  2013 Oct-Dec
  4 in total

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