Literature DB >> 1620102

Riboflavin operon of Bacillus subtilis: unusual symmetric arrangement of the regulatory region.

Y V Kil1, V N Mironov, R A Kreneva, D A Perumov.   

Abstract

Seventeen cis-dominant mutations leading to riboflavin overproduction in Bacillus subtilis were localized to the region between nucleotides +37 and +159 relative to the transcription initiation site of the riboflavin operon. This region displays an unusual structure for regulatory sequences. The main part of it represents clusters of A/T and G/C-rich sequences that symmetrically blank a short inverted repeat.

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Year:  1992        PMID： 1620102     DOI： 10.1007/bf00265448

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  17 in total

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Authors:  L Van Kaer; M Van Montagu; P Dhaese
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8.  Genetic mapping of regulatory mutations of Bacillus subtilis riboflavin operon.

Authors:  R A Kreneva; D A Perumov
Journal:  Mol Gen Genet       Date:  1990-07

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
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  17 in total

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Review 4.  Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.

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5.  Flavoproteins are potential targets for the antibiotic roseoflavin in Escherichia coli.

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6.  Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC.

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Review 7.  Emerging applications of riboswitches in chemical biology.

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8.  Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.

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9.  Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw.

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