Literature DB >> 16192410

The relevance of empirical research in bioethics.

Franklin G Miller1, David Wendler.   

Abstract

Empirical research related to ethical issues in clinical research has grown dramatically in recent years. However, little attention has been devoted to the ethical relevance of the findings from this research. In order to examine the value and limitations of ethics-related empirical research, we discuss 3 case studies involving research with stored biological samples, placebo-controlled trials, and the idea of the therapeutic misconception.

Mesh:

Year:  2005        PMID: 16192410      PMCID: PMC2632190          DOI: 10.1093/schbul/sbj004

Source DB:  PubMed          Journal:  Schizophr Bull        ISSN: 0586-7614            Impact factor:   9.306


  22 in total

1.  The ethics of placebo-controlled trials--a middle ground.

Authors:  E J Emanuel; F G Miller
Journal:  N Engl J Med       Date:  2001-09-20       Impact factor: 91.245

2.  What makes placebo-controlled trials unethical?

Authors:  Franklin G Miller; Howard Brody
Journal:  Am J Bioeth       Date:  2002       Impact factor: 11.229

3.  When argument fails.

Authors:  Charles Weijer
Journal:  Am J Bioeth       Date:  2002       Impact factor: 11.229

4.  The debate over research on stored biological samples: what do sources think?

Authors:  Dave Wendler; Ezekiel Emanuel
Journal:  Arch Intern Med       Date:  2002-07-08

5.  Views of American oncologists about the purposes of clinical trials.

Authors:  Steven Joffe; Jane C Weeks
Journal:  J Natl Cancer Inst       Date:  2002-12-18       Impact factor: 13.506

6.  Placebo-controlled trials in psychiatric research: an ethical perspective.

Authors:  F G Miller
Journal:  Biol Psychiatry       Date:  2000-04-15       Impact factor: 13.382

7.  Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 1: ethical and scientific issues.

Authors:  R Temple; S S Ellenberg
Journal:  Ann Intern Med       Date:  2000-09-19       Impact factor: 25.391

8.  High rate of consent to bank biologic samples for future research: the Eastern Cooperative Oncology Group experience.

Authors:  Thomas Malone; Paul J Catalano; Peter J O'Dwyer; Bruce Giantonio
Journal:  J Natl Cancer Inst       Date:  2002-05-15       Impact factor: 13.506

9.  Consent to the use of stored DNA for genetics research: a survey of attitudes in the Jewish population.

Authors:  M D Schwartz; K Rothenberg; L Joseph; J Benkendorf; C Lerman
Journal:  Am J Med Genet       Date:  2001-02-01

10.  Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials: an analysis of the Food and Drug Administration database.

Authors:  A Khan; H A Warner; W A Brown
Journal:  Arch Gen Psychiatry       Date:  2000-04
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  6 in total

Review 1.  Emerging empirical evidence on the ethics of schizophrenia research.

Authors:  Laura B Dunn; Philip J Candilis; Laura Weiss Roberts
Journal:  Schizophr Bull       Date:  2005-10-19       Impact factor: 9.306

2.  How should debriefing be undertaken in web-based studies? Findings from a randomized controlled trial.

Authors:  Jim McCambridge; Kypros Kypri; Amanda Wilson
Journal:  J Med Internet Res       Date:  2012-11-16       Impact factor: 5.428

3.  Empirical research in medical ethics: how conceptual accounts on normative-empirical collaboration may improve research practice.

Authors:  Sabine Salloch; Jan Schildmann; Jochen Vollmann
Journal:  BMC Med Ethics       Date:  2012-04-13       Impact factor: 2.652

4.  Research across the disciplines: a road map for quality criteria in empirical ethics research.

Authors:  Marcel Mertz; Julia Inthorn; Günter Renz; Lillian Geza Rothenberger; Sabine Salloch; Jan Schildmann; Sabine Wöhlke; Silke Schicktanz
Journal:  BMC Med Ethics       Date:  2014-03-01       Impact factor: 2.652

5.  The use of deception in public health behavioral intervention trials: a case study of three online alcohol trials.

Authors:  Jim McCambridge; Kypros Kypri; Preben Bendtsen; John Porter
Journal:  Am J Bioeth       Date:  2013       Impact factor: 11.229

6.  Therapeutic Misconception in Psychiatry Research: A Systematic Review.

Authors:  Ivan Sk Thong; Meng Yee Foo; Min Yi Sum; Benjamin Capps; Tih-Shih Lee; Calvin Ho; Kang Sim
Journal:  Clin Psychopharmacol Neurosci       Date:  2016-02-29       Impact factor: 2.582

  6 in total

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