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Literature DB >> 1617949

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring.

Abstract

The pharmacokinetic software package MW/Pharm offers an interactive, user-friendly program which gives rapid answers in clinical practice. It comprises a database with pharmacokinetic parameters of 180 drugs, a medication history database, and procedures for an individual drug dosage regimen calculation. The included curve-fitting facilities allow estimation of pharmacokinetic parameters on the basis of medication history, taking into account a varying status of the patient with respect to body weight and kidney function, optionally using a Bayesian procedure. The module KinBes performs the evaluation of bioavailability studies, including various methods, and an extensive statistical evaluation of bioequivalence.

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Year: 1992 PMID： 1617949 DOI： 10.1016/0010-4825(92)90011-b

Source DB: PubMed Journal: Comput Biol Med ISSN： 0010-4825 Impact factor: 4.589

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Cited

94 in total

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2. Performance of an iterative two-stage bayesian technique for population pharmacokinetic analysis of rich data sets.

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3. Pharmacokinetics and protein binding of cefazolin in morbidly obese patients.

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5. The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30 mg oxazepam.

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6. Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.

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Journal: Clin Pharmacol Ther Date: 2019-12-11 Impact factor: 6.875

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring.

Review 1. Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

2. Performance of an iterative two-stage bayesian technique for population pharmacokinetic analysis of rich data sets.

3. Pharmacokinetics and protein binding of cefazolin in morbidly obese patients.

4. High voriconazole trough levels in relation to hepatic function: how to adjust the dosage?

5. The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30 mg oxazepam.

6. Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.

7. Association between CYP1A2 activity and riluzole clearance in patients with amyotrophic lateral sclerosis.

8. Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks.

9. Continuous infusion of ceftazidime in febrile neutropenic patients with acute myeloid leukemia.

10. Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts.