Literature DB >> 1612966

Improved pain management with daily nursing intervention during radiation therapy for head and neck carcinoma.

N A Janjan1, D E Weissman, A Pahule.   

Abstract

This study evaluated the response to a defined mouth care and analgesic treatment protocol for oropharyngeal mucositis in patients undergoing radiation therapy for head and neck carcinoma. Nineteen patients completed a 15 question pain survey before each radiation treatment. Patients were given instructions on the use of mouthwashes and a three-step analgesic protocol: acetaminophen, acetaminophen with codeine suspension, and oral morphine (20 mg/mL) for mild, moderate, and severe pain, respectively. Patients were seen daily by a radiation therapy nurse who reviewed the survey and prompt changes in the prescribed analgesic regimen were then made by a physician. Marked differences in control of pain related to radiation mucositis were observed when compared to patients from our prior study who used the same daily survey but had only sporadic nursing intervention and no analgesic protocol. Patients having daily nursing intervention reported fewer days of moderate/severe pain, had less pain throughout the day, and noted less disturbance in sleep, eating, and energy level. Weight loss of greater than 5 kg was noted in only three patients. Analgesics were used on 77% of treatment days and relieved all or most of the pain in 94% of these days. Daily review of a symptom survey by a radiation therapy nurse, combined with a well-defined strategy for mouth care, and analgesics results in improved pain management of radiation induced oropharyngeal mucositis because of prompt attention to patient needs. Future trials should incorporate defined strategies for oral care and analgesic use to control for possible bias in assessing efficacy.

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Year:  1992        PMID: 1612966     DOI: 10.1016/0360-3016(92)90024-c

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  6 in total

1.  A simple and effective daily pain management method for patients receiving radiation therapy for painful bone metastases.

Authors:  Regiane S Andrade; Julian W Proctor; Robert Slack; Ursula Marlowe; Karlotta R Ashby; Larry L Schenken
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-02-19       Impact factor: 7.038

Review 2.  [Prevention and therapy of acute radiation-related morbidity of the skin and mucosa. II, Recommendations of the literature].

Authors:  J S Zimmermann; P Niehoff; R Wilhelm; R Schneider; G Kovács; B Kimmig
Journal:  Strahlenther Onkol       Date:  1998-04       Impact factor: 3.621

Review 3.  Systematic review of basic oral care for the management of oral mucositis in cancer patients.

Authors:  Deborah B McGuire; Janet S Fulton; Jumin Park; Carlton G Brown; M Elvira P Correa; June Eilers; Sharon Elad; Faith Gibson; Loree K Oberle-Edwards; Joanne Bowen; Rajesh V Lalla
Journal:  Support Care Cancer       Date:  2013-09-10       Impact factor: 3.603

Review 4.  [The therapeutic management of radiogenic oral mucositis].

Authors:  W Dörr; I Dölling-Jochem; M Baumann; T Herrmann
Journal:  Strahlenther Onkol       Date:  1997-04       Impact factor: 3.621

5.  Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts.

Authors:  Long-Hui Cao; Hui-Ting Li; Wen-Qian Lin; Hong-Ying Tan; Lan Xie; Zhong-Jian Zhong; Jian-Hua Zhou
Journal:  Sci Rep       Date:  2016-01-05       Impact factor: 4.379

Review 6.  Status of Treatment and Prophylaxis for Radiation-Induced Oral Mucositis in Patients With Head and Neck Cancer.

Authors:  Shiyu Liu; Qin Zhao; Zhuangzhuang Zheng; Zijing Liu; Lingbin Meng; Lihua Dong; Xin Jiang
Journal:  Front Oncol       Date:  2021-03-18       Impact factor: 6.244

  6 in total

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