Literature DB >> 16118240

Octogenarians undergoing cardiac surgery outlive their peers: a case for early referral.

S C Stoica1, F Cafferty, J Kitcat, R J F Baskett, M Goddard, L D Sharples, F C Wells, S A M Nashef.   

Abstract

OBJECTIVE: To examine short and long term outcomes of octogenarians having heart operations and to analyse the interaction between patient and treatment factors.
METHODS: Multivariate analysis of prospectively collected data and a survival comparison with an age and sex matched national population. The outcomes were base in-hospital mortality, risk stratified by logistic EuroSCORE (European system for cardiac operative risk evaluation), and long term survival.
RESULTS: 12,461 consecutive patients (706 over 80 years) operated on between 1996 and 2003 in a regional UK unit were studied. Octogenarians more often had impaired ventricular function, pulmonary hypertension, and valve operations. They also included a higher proportion of women, had a higher serum creatinine concentration, and had a trend towards more unstable angina. Younger patients had a higher prevalence of previous cardiac operation, previous myocardial infarction, and diabetes. The in-hospital mortality rate was 3.9% for all patients (EuroSCORE predicted 6.1%, p < 0.001) and 9.8% for octogenarians (predicted 14.1%, p = 0.002). Long bypass time and non-elective surgery increased the risk of death above EuroSCORE prediction in both groups. A greater proportion of octogenarians stayed in intensive care more than 24 hours (37% v 23%, p < 0.001). Long term survival was significantly better in the study patients than in a general population with the same age-sex distribution (survival rate at five years 82.1% v 55.9%, p < 0.001).
CONCLUSIONS: Cardiac surgery in a UK population of octogenarians produced excellent results. Elective referrals should be encouraged in all age groups.

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Year:  2005        PMID: 16118240      PMCID: PMC1860849          DOI: 10.1136/hrt.2005.064451

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  14 in total

1.  Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network.

Authors:  K P Alexander; K J Anstrom; L H Muhlbaier; R D Grosswald; P K Smith; R H Jones; E D Peterson
Journal:  J Am Coll Cardiol       Date:  2000-03-01       Impact factor: 24.094

2.  Preoperative risk prediction and intraoperative events in cardiac surgery.

Authors:  Serban C Stoica; Linda D Sharples; Ishtaq Ahmed; François Roques; Stephen R Large; Samer A M Nashef
Journal:  Eur J Cardiothorac Surg       Date:  2002-01       Impact factor: 4.191

3.  Cardiac surgery in octogenarians; peri-operative outcome and long-term results.

Authors:  P Kolh; A Kerzmann; L Lahaye; P Gerard; R Limet
Journal:  Eur Heart J       Date:  2001-07       Impact factor: 29.983

4.  Logistic or additive EuroSCORE for high-risk patients?

Authors:  Philippe Michel; Francois Roques; Samer A M Nashef
Journal:  Eur J Cardiothorac Surg       Date:  2003-05       Impact factor: 4.191

5.  Quality of life after cardiac surgery in the elderly.

Authors:  R P Mittermair; L C Müller
Journal:  J Cardiovasc Surg (Torino)       Date:  2002-02       Impact factor: 1.888

6.  European system for cardiac operative risk evaluation (EuroSCORE).

Authors:  S A Nashef; F Roques; P Michel; E Gauducheau; S Lemeshow; R Salamon
Journal:  Eur J Cardiothorac Surg       Date:  1999-07       Impact factor: 4.191

7.  Cost, outcome, and functional status in octogenarians and septuagenarians after cardiac surgery.

Authors:  Milo Engoren; Cynthia Arslanian-Engoren; Donna Steckel; Julie Neihardt; Nancy Fenn-Buderer
Journal:  Chest       Date:  2002-10       Impact factor: 9.410

8.  Trial of invasive versus medical therapy in elderly patients with chronic symptomatic coronary-artery disease (TIME): a randomised trial.

Authors: 
Journal:  Lancet       Date:  2001-09-22       Impact factor: 79.321

9.  Survival after coronary revascularization in the elderly.

Authors:  Michelle M Graham; William A Ghali; Peter D Faris; P Diane Galbraith; Colleen M Norris; Merril L Knudtson
Journal:  Circulation       Date:  2002-05-21       Impact factor: 29.690

10.  Surgeon specific mortality in adult cardiac surgery: comparison between crude and risk stratified data.

Authors:  Ben Bridgewater; Anthony D Grayson; Mark Jackson; Nicholas Brooks; Geir J Grotte; Daniel J M Keenan; Russell Millner; Brian M Fabri; Mark Jones
Journal:  BMJ       Date:  2003-07-05
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  8 in total

1.  Valve surgery in octogenarians: in-hospital and long-term outcomes.

Authors:  Eduardo Bossone; Giuseppe Di Benedetto; Alessandro Frigiola; Giannignazio Luigi Carbone; Antonello Panza; Silvia Cirri; Andrea Ballotta; Stefano Messina; Saverio Rega; Rodolfo Citro; Santi Trimarchi; Jianming Fang; Paolo Righini; Alessandro Distante; Kim A Eagle; Rajendra H Mehta
Journal:  Can J Cardiol       Date:  2007-03-01       Impact factor: 5.223

2.  Cardiac surgery in the very elderly: it isn't all about survival.

Authors:  Ishtiaq Ali Rahman; Simon Kendall
Journal:  Br J Cardiol       Date:  2020-03-04

Review 3.  Cardiac surgery in the elderly patient.

Authors:  Ivar Friedrich; Andreas Simm; Joachim Kötting; Frank Thölen; Burkhard Fischer; Rolf-Edgar Silber
Journal:  Dtsch Arztebl Int       Date:  2009-06-19       Impact factor: 5.594

Review 4.  Coronary artery bypass surgery in elderly people.

Authors:  Arun Natarajan; Samad Samadian; Stephen Clark
Journal:  Postgrad Med J       Date:  2007-03       Impact factor: 2.401

Review 5.  Minimally invasive aortic valve replacement in high risk patient groups.

Authors:  Daniel Fudulu; Harriet Lewis; Umberto Benedetto; Massimo Caputo; Gianni Angelini; Hunaid A Vohra
Journal:  J Thorac Dis       Date:  2017-06       Impact factor: 2.895

6.  Coronary artery bypass grafting: 30-day operative morbidity analysis in 1046 patients.

Authors:  Nizar R Alwaqfi; Yousef S Khader; Khaled S Ibrahim; Fahmi M Eqab
Journal:  J Clin Med Res       Date:  2012-07-20

7.  Concomitant ablation of atrial fibrillation in octogenarians: an observational study.

Authors:  Herko Grubitzsch; Sven Beholz; Pascal M Dohmen; Simon Dushe; Wolfgang Konertz
Journal:  J Cardiothorac Surg       Date:  2008-04-29       Impact factor: 1.637

8.  Evaluating the effect of healthcare providers on the clinical path of heart failure patients through a semi-Markov, multi-state model.

Authors:  Francesca Gasperoni; Francesca Ieva; Anna Maria Paganoni; Christopher H Jackson; Linda Sharples
Journal:  BMC Health Serv Res       Date:  2020-06-12       Impact factor: 2.655

  8 in total

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