A study of the prevalence of iron deficiency and its related factors in blood donors of Yazd, Iran, 2003.

Iron deficiency anaemia is an important limiting factor for the number of donations in regular donors. Limited data is available on the iron status in Iranian donors. This study was conducted to evaluate the prevalence of iron deficiency and its related factors in blood donors at Yazd blood transfusion centre, Iran. In this descriptive study, 337 persons accepted for donation in 2003 were selected randomly. Haemoglobin, serum iron, total iron-binding capacity and ferritin concentrations were measured. Results showed that the prevalence of reduction in iron stores increased with an increase in the number of donations (P = 0.0001), such that reduction in iron stores was seen in all regular female donors (100%) and 48% of regular male blood donors. The prevalence of iron deficiency in female and male regular donors was 78 and 28%, whereas 55.6 and 16% of these donors had iron deficiency anaemia. Just one blood donation resulted in a significant increase in the prevalence of iron deficiency in women (P < 0.05), but in men, a significant increase was seen only in regular donors (P < 0.05). It is therefore recommended that blood donors should be educated about iron deficiency, and research studies should be performed to determine the best method of iron supplementation with minimal complications for all regular blood donors and women of childbearing age on their first donation.