Literature DB >> 1608979

Eight base changes are sufficient to convert a leucine-inserting tRNA into a serine-inserting tRNA.

J Normanly1, T Ollick, J Abelson.   

Abstract

Each aminoacyl-tRNA synthetase must functionally distinguish its cognate tRNAs from all others. We have determined the minimum number of changes required to transform a leucine amber suppressor tRNA to serine identity. Eight changes are required. These are located in the acceptor stem and in the D stem.

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Year:  1992        PMID: 1608979      PMCID: PMC49356          DOI: 10.1073/pnas.89.12.5680

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  39 in total

1.  A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 A.

Authors:  S Cusack; C Berthet-Colominas; M Härtlein; N Nassar; R Leberman
Journal:  Nature       Date:  1990-09-20       Impact factor: 49.962

2.  Sequence-specific recognition of double helical nucleic acids by proteins.

Authors:  N C Seeman; J M Rosenberg; A Rich
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

3.  Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase.

Authors:  M A Rould; J J Perona; T A Steitz
Journal:  Nature       Date:  1991-07-18       Impact factor: 49.962

4.  Discrimination between glutaminyl-tRNA synthetase and seryl-tRNA synthetase involves nucleotides in the acceptor helix of tRNA.

Authors:  M J Rogers; D Söll
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

5.  Construction of Escherichia coli amber suppressor tRNA genes. II. Synthesis of additional tRNA genes and improvement of suppressor efficiency.

Authors:  L G Kleina; J M Masson; J Normanly; J Abelson; J H Miller
Journal:  J Mol Biol       Date:  1990-06-20       Impact factor: 5.469

6.  Changing the identity of a tRNA by introducing a G-U wobble pair near the 3' acceptor end.

Authors:  W H McClain; K Foss
Journal:  Science       Date:  1988-05-06       Impact factor: 47.728

Review 7.  tRNA identity.

Authors:  J Normanly; J Abelson
Journal:  Annu Rev Biochem       Date:  1989       Impact factor: 23.643

8.  Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli.

Authors:  E Amann; J Brosius; M Ptashne
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

9.  An Escherichia coli tyrosine transfer RNA is a leucine-specific transfer RNA in the yeast Saccharomyces cerevisiae.

Authors:  H Edwards; V Trézéguet; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

10.  Systematic alterations in the anticodon arm make tRNA(Glu)-Suoc a more efficient suppressor.

Authors:  L A Raftery; M Yarus
Journal:  EMBO J       Date:  1987-05       Impact factor: 11.598

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  33 in total

1.  An engineered class I transfer RNA with a class II tertiary fold.

Authors:  T A Nissan; B Oliphant; J J Perona
Journal:  RNA       Date:  1999-03       Impact factor: 4.942

2.  The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate analogue reveals a conformational switch in the active site.

Authors:  S Cusack; A Yaremchuk; M Tukalo
Journal:  EMBO J       Date:  1996-06-03       Impact factor: 11.598

3.  Variant minihelix RNAs reveal sequence-specific recognition of the helical tRNA(Ser) acceptor stem by E.coli seryl-tRNA synthetase.

Authors:  M E Saks; J R Sampson
Journal:  EMBO J       Date:  1996-06-03       Impact factor: 11.598

Review 4.  Structure, function and evolution of seryl-tRNA synthetases: implications for the evolution of aminoacyl-tRNA synthetases and the genetic code.

Authors:  M Härtlein; S Cusack
Journal:  J Mol Evol       Date:  1995-05       Impact factor: 2.395

Review 5.  Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.

Authors:  Wei Wan; Jeffery M Tharp; Wenshe R Liu
Journal:  Biochim Biophys Acta       Date:  2014-03-12

6.  Identity elements of human tRNA(Leu): structural requirements for converting human tRNA(Ser) into a leucine acceptor in vitro.

Authors:  K Breitschopf; T Achsel; K Busch; H J Gross
Journal:  Nucleic Acids Res       Date:  1995-09-25       Impact factor: 16.971

7.  Eukaryotic selenocysteine inserting tRNA species support selenoprotein synthesis in Escherichia coli.

Authors:  C Baron; C Sturchler; X Q Wu; H J Gross; A Krol; A Böck
Journal:  Nucleic Acids Res       Date:  1994-06-25       Impact factor: 16.971

8.  Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes.

Authors:  Xiaoling Xu; Yi Shi; Xiang-Lei Yang
Journal:  Structure       Date:  2013-10-03       Impact factor: 5.006

9.  Molecular reconstruction of a fungal genetic code alteration.

Authors:  Denisa D Mateus; João A Paredes; Yaiza Español; Lluís Ribas de Pouplana; Gabriela R Moura; Manuel A S Santos
Journal:  RNA Biol       Date:  2013-04-17       Impact factor: 4.652

10.  Contributions of discrete tRNA(Ser) domains to aminoacylation by E.coli seryl-tRNA synthetase: a kinetic analysis using model RNA substrates.

Authors:  J R Sampson; M E Saks
Journal:  Nucleic Acids Res       Date:  1993-09-25       Impact factor: 16.971

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