Literature DB >> 2452483

Changing the identity of a tRNA by introducing a G-U wobble pair near the 3' acceptor end.

W H McClain1, K Foss.   

Abstract

Although the genetic code for protein was established in the 1960's, the basis for amino acid identity of transfer RNA (tRNA) has remained unknown. To investigate the identity of a tRNA, the nucleotides at three computer-identified positions in tRNAPhe (phenylalanine tRNA) were replaced with the corresponding nucleotides from tRNAAla (alanine tRNA). The identity of the resulting tRNA, when examined as an amber suppressor in Escherichia coli, was that of tRNAAla.

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Year:  1988        PMID： 2452483     DOI： 10.1126/science.2452483

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  121 in total

1.  Correlation of deformability at a tRNA recognition site and aminoacylation specificity.

Authors:  K Y Chang; G Varani; S Bhattacharya; H Choi; W H McClain
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-12       Impact factor: 11.205

Review 2.  The G x U wobble base pair. A fundamental building block of RNA structure crucial to RNA function in diverse biological systems.

Authors:  G Varani; W H McClain
Journal:  EMBO Rep       Date:  2000-07       Impact factor: 8.807

3.  Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains.

Authors:  J W Chihade; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

4.  Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging.

Authors:  K Hanawa-Suetsugu; V Bordeau; H Himeno; A Muto; B Felden
Journal:  Nucleic Acids Res       Date:  2001-11-15       Impact factor: 16.971

5.  Determinants on tmRNA for initiating efficient and precise trans-translation: some mutations upstream of the tag-encoding sequence of Escherichia coli tmRNA shift the initiation point of trans-translation in vitro.

Authors:  S Lee; M Ishii; T Tadaki; A Muto; H Himeno
Journal:  RNA       Date:  2001-07       Impact factor: 4.942

6.  SmpB functions in various steps of trans-translation.

Authors:  Kyoko Hanawa-Suetsugu; Mitsuru Takagi; Hachiro Inokuchi; Hyouta Himeno; Akira Muto
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

7.  Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G.U wobble base pair at 1.16 A resolution.

Authors:  U Mueller; H Schübel; M Sprinzl; U Heinemann
Journal:  RNA       Date:  1999-05       Impact factor: 4.942

8.  Enzymatic aminoacylation of an eight-base-pair microhelix with histidine.

Authors:  C Francklyn; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

9.  Importance of the reverse Hoogsteen base pair 54-58 for tRNA function.

Authors:  Ekaterina I Zagryadskaya; Felix R Doyon; Sergey V Steinberg
Journal:  Nucleic Acids Res       Date:  2003-07-15       Impact factor: 16.971

10.  Acceptor end binding domain interactions ensure correct aminoacylation of transfer RNA.

Authors:  I Weygand-Durasević; E Schwob; D Söll
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205
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