Literature DB >> 16061377

The enigma of coproporphyrinogen oxidase: how does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups?

Timothy D Lash1.   

Abstract

A new mechanism is proposed to explain how coproporphyrinogen oxidase performs two oxidative decarboxylations on a porphyrinogen substrate without the aid of cofactors or metal ions in the presence of molecular oxygen.

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Year:  2005        PMID： 16061377     DOI： 10.1016/j.bmcl.2005.07.010

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  11 in total

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Review 2.  One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans.

Authors:  Iqbal Hamza; Harry A Dailey
Journal:  Biochim Biophys Acta       Date:  2012-05-08

3.  Reactions of Ferrous Coproheme Decarboxylase (HemQ) with O2 and H2O2 Yield Ferric Heme b.

Authors:  Bennett R Streit; Arianna I Celis; Krista Shisler; Kenton R Rodgers; Gudrun S Lukat-Rodgers; Jennifer L DuBois
Journal:  Biochemistry       Date:  2016-12-16       Impact factor: 3.162

4.  Role of aspartate 400, arginine 262, and arginine 401 in the catalytic mechanism of human coproporphyrinogen oxidase.

Authors:  Jason R Stephenson; Julie A Stacey; Justin B Morgenthaler; Jon A Friesen; Timothy D Lash; Marjorie A Jones
Journal:  Protein Sci       Date:  2007-01-22       Impact factor: 6.725

Review 5.  Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.

Authors:  Harry A Dailey; Tamara A Dailey; Svetlana Gerdes; Dieter Jahn; Martina Jahn; Mark R O'Brian; Martin J Warren
Journal:  Microbiol Mol Biol Rev       Date:  2017-01-25       Impact factor: 11.056

6.  Unusual Peroxide-Dependent, Heme-Transforming Reaction Catalyzed by HemQ.

Authors:  Arianna I Celis; Bennett R Streit; Garrett C Moraski; Ravi Kant; Timothy D Lash; Gudrun S Lukat-Rodgers; Kenton R Rodgers; Jennifer L DuBois
Journal:  Biochemistry       Date:  2015-06-23       Impact factor: 3.162

Review 7.  Regulation of Heme Synthesis by Mitochondrial Homeostasis Proteins.

Authors:  Yvette Y Yien; Mark Perfetto
Journal:  Front Cell Dev Biol       Date:  2022-06-27

8.  Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin.

Authors:  Harry A Dailey; Svetlana Gerdes; Tamara A Dailey; Joseph S Burch; John D Phillips
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-02       Impact factor: 11.205

Review 9.  Erythroid heme biosynthesis and its disorders.

Authors:  Harry A Dailey; Peter N Meissner
Journal:  Cold Spring Harb Perspect Med       Date:  2013-04-01       Impact factor: 6.915

10.  Recent advances in the biosynthesis of modified tetrapyrroles: the discovery of an alternative pathway for the formation of heme and heme d 1.

Authors:  Shilpa Bali; David J Palmer; Susanne Schroeder; Stuart J Ferguson; Martin J Warren
Journal:  Cell Mol Life Sci       Date:  2014-02-11       Impact factor: 9.261
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